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Professor John Murphy

Pure and Applied Chemistry

Personal statement

I am an organic chemist and my research group revels in exploring chemical reactivity in synthesis and in biology. We have a particular interest in electron transfer reactions and in radical chemistry, but are generally interested in mechanisms of organic reactions.

Read more about my research group at

I was born in Dublin and educated at Trinity College, Dublin (BA) and the University of Cambridge (PhD). I obtained my DSc in 2002.

After my PhD, I held Fellowships at the University of Alberta and the University of Oxford. I moved to the University of Nottingham as Lecturer, and was promoted to Reader there.

I moved to my current position as Merck-Pauson Professor of Chemistry at the University of Strathclyde in 1995.

I was visiting Professor at a number of institutions:

  1. l’Université d’Aix Marseille 1996
  2. NAIST, Japan, 2001
  3. Université Pierre et Marie Curie, Paris, 2004
  4. Universite Claude Bernard Lyon 1, 2017

I also was Visiting Fellow to the Australian National University in 1995 and 2007. I held a Royal Society Leverhulme Senior Research Fellowship in 2001.

I was elected Fellow of the Royal Society of Edinburgh (National Academy of  Scotland) in 2001. 

I was Director of the Glasgow Centre for Physical Organic Chemistry (GCPOC) 2008-2013.

From August 2006 - August 2008, I was Director of WestCHEM, the newly formed integrated Research School in Chemistry for the West of Scotland.

From 2013-2016, I was Head of Department of Pure and Applied Chemistry


2016 C W Rees Award for Heterocyclic chemistry (Royal Society of Chemistry)

2012 Bader Award  (Royal Society of Chemistry)


KOtBu as a single electron donor? Revisiting the halogenation of alkanes with CBr4 and CCl4
Emery Katie J., Young Allan, Arokianathar J. Norman, Tuttle Tell, Murphy John A.
Molecules Vol 23, (2018)
A computational study of anionic alkoxide–allene and amide–allene cyclizations
Cumine Florimond, Young Allan, Reissig Hans-Ulrich, Tuttle Tell, Murphy John A.
European Journal of Organic Chemistry Vol 2017, pp. 6867-6871, (2017)
Selectively targeting the kinome-conserved lysine of PI3K (delta) as a general approach to covalent kinase inhibition
Campos Sébastien André, Murphy John, Dalton Samuel, Dittus Lars , Thomas Daniel, Convery Maire, Nunes Joao, Bush Jacob, Evans John, Werner Thilo, Bantscheff Marcus
Journal of American Chemical Society, (2017)
Evidence of single electron transfer from the enolate anion of an N,N'-dialkyldiketopiperazine additive in BHAS coupling reactions
Emery Katie J., Tuttle Tell, Murphy John A.
Organic and Biomolecular Chemistry Vol 15, pp. 8810-8819, (2017)
Electron transfer and hydride transfer pathways in the Stoltz-Grubbs reducing system (KOtBu-Et3SiH)
Smith Andrew J., Young Allan, Rohrbach Simon, O'Connor Erin F., Allison Mark, Wang Hong-Shuang, Poole Darren L., Tuttle Tell, Murphy John A.
Angewandte Chemie Vol 56, pp. 13747–13751, (2017)
A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling
Cumine Florimond, Zhou Shengze, Tuttle Tell, Murphy John A.
Organic and Biomolecular Chemistry Vol 15, pp. 3324 - 3336, (2017)

more publications

Research interests

His chemical interests are in mechanistic and synthetic chemistry, in reactive intermediates and in the development of new reactions.

Professional activities

ESOR (European Symposium on Organic Reactivity)
Royal Society International Exchanges Panel 2017-2019 (Event)
Evolution of Organic Electron Donors
Invited speaker
Transition metal-free coupling reactions
Invited speaker
Transition metal-free coupling reactions
Invited speaker
12th International Symposium on Organic Free Radicals (ISOFR)
Keynote/plenary speaker

more professional activities


Industrial CASE Account - University of Strathclyde 2017 | Adams, Scott
Kerr, William (Principal Investigator) Murphy, John (Co-investigator)
Period 01-Oct-2017 - 01-Oct-2021
Development of new sustainable molecular transformations with alkali/alkaline earth metal reagents
Murphy, John (Principal Investigator)
Period 01-Mar-2018 - 28-Feb-2020
Funding for PhD studentship raised from industry
Murphy, John (Principal Investigator)
I requested and was granted funding of these 4 studentships, to be supervised by collagues in assoiation with this grant
Period 01-Sep-2008 - 31-Aug-2012
Industrial Case Account 2015 | Smith, Andrew
Murphy, John (Principal Investigator) Nelson, David (Co-investigator) Smith, Andrew (Research Co-investigator)
Period 01-Oct-2015 - 01-Oct-2019
Physical Organic Chemistry: Opportunities In Synthesis, Materials And Pharmaceuticals (Science And Innovation Award) | Idziak, Christopher
Tuttle, Christopher (Principal Investigator) Murphy, John (Co-investigator)
Period 01-Oct-2009 - 14-Jan-2014
Doctoral Training Partnership (DTA - University of Strathclyde) | Allison, Mark
Murphy, John (Principal Investigator) Tuttle, Christopher (Co-investigator) Allison, Mark (Research Co-investigator)
Period 01-Oct-2014 - 01-Apr-2018

more projects


Pure and Applied Chemistry
Thomas Graham Building

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