Dr Karla Neves
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
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Prize And Awards
- Images of Research 2025 - Category winner - People & Possibility
- Recipient
- 2025
- Scottish Microscopy Society 2022 Image Competition Images of Research
- Recipient
- 12/2022
- Best Oral Presentation (Post-Doctoral category)
- Recipient
- 2021
- Paul Dudley White International Scholar Award
- Recipient
- 2020
- Stephanie Watts Career Development Award
- Recipient
- 2020
- Best Poster Presentation (Post-Doctoral category)
- Recipient
- 2019
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Publications
- Renal-vascular axis : Unmasking its role in VEGF-inhibitor vascular toxicity in cancer patients
- Whelan Grace, Neves Karla
- British Journal of Pharmacology (2026)
- https://doi.org/10.1111/bph.70378
- Salt-induced vascular damage in hypertension involves redox activation of PARP/TRPM2 signalling and inflammasome assembly
- Alves-Lopes Rheure, Neves Karla B, Mary Sheon, Graham Delyth, Montezano Augusto C, Delles Christian, Touyz Rhian M
- American Journal of Hypertension Vol 38, pp. 788-796 (2025)
- https://doi.org/10.1093/ajh/hpaf071
- Humanising nanotoxicology : replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard
- Fraser Roma, Campbell Keira, Pokorski Pawel, Mackinnon Eve, McAllister Katie, Neves Karla B, Murphy Fiona
- Frontiers in Bioengineering and Biotechnology Vol 13 (2025)
- https://doi.org/10.3389/fbioe.2025.1526808
- P169 VEGF inhibition-induced PARP overactivation leads to endothelial dysfunction and inflammation : role of Sirtuin 1 signalling
- Neves Karla, Alves-Lopes Rheure, Montezano Augusto, Touyz Rhian
- (2024)
- https://doi.org/10.1097/01.hjh.0001063548.35277.58
- Editorial: The interplay between oxidative stress, immune cells and inflammation in cardiovascular diseases
- Nosalski R, Siedlinski M, Neves K B, Monaco C
- Frontiers in Cardiovascular Medicine Vol 11 (2024)
- https://doi.org/10.3389/fcvm.2024.1385809
- Vasoprotective effects of NOX4 are mediated via polymerase and transient receptor potential melastatin 2 cation channels in endothelial cells
- Alves-Lopes Rheure, Lacchini Silvia, Neves Karla B, Harvey Adam, Montezano Augusto C, Touyz Rhian M
- Journal of Hypertension Vol 41, pp. 1389-1400 (2023)
- https://doi.org/10.1097/HJH.0000000000003478
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Research Interests
Her research interests are in understanding molecular and vascular mechanisms associated with cardiovascular and metabolic diseases, with a particular interest in the cardiovascular effects of anti-cancer drugs. She has a large expertise in vascular function, vascular smooth muscle cells and endothelial pathways, nitric oxide and oxidative stress, using a multidisciplinary approach with both in vitro and in vivo models of vascular function in health and disease.
Professional Activities
- Scottish Cardiovascular Forum 2026
- Organiser
- 21/3/2026
- University of Strathclyde 3Rs & Culture of Care Day
- Participant
- 4/12/2025
- The role of microRNA-26b in cardiovascular calcification
- External Examiner
- 4/11/2025
- Global Career Journeys Interview
- Interviewee
- 10/2025
- International Society of Hypertension - ISH 2024
- Organiser
- 20/9/2025
- Jean Carlos Lipreri da Silva
- Host
- 1/8/2025
Projects
- Partnership Seed Grant Application
- Devlin, Jon (Principal Investigator) Clift, Lee (Co-investigator) Dombi, Erzsebet (Co-investigator) Goodfellow, Martin (Co-investigator) Humphrey, Suzanne (Co-investigator) Huq, Molly (Co-investigator) Murphy, Fiona (Co-investigator) Neves, Karla (Co-investigator) Sprick, Seb (Co-investigator) Wu, Yue (Co-investigator) Young, David (Co-investigator)
- 22-Jan-2025 - 31-Jan-2027
- The Role of O-GlcNAcylation on the endothelial cell phenotype induced by VEGF inhibitors: study on hypertensive cancer patients
- Neves, Karla (CoPI) Januario da Costa, Tiago (CoPI) Lipreri da Silva, Jean Carlos (Fellow)
- Postdoctoral Fellowship from The National Council for Scientific and Technological Development (CNPq) - USD 191.768,34
- 01-Jan-2025 - 31-Jan-2026
- O-GlcNAcylation and VEGF inhibitors: impact on vascular cell phenotype and hypertension
- Neves, Karla (Principal Investigator)
- 01-Jan-2025 - 31-Jan-2027
- Innovating Cancer Research: New Models, New Hope
- Neves, Karla (Co-investigator) Murphy, Fiona (Co-investigator)
- NC3Rs Public Engagement Awards – 20-year anniversary (£2,000)
- 01-Jan-2024 - 28-Jan-2025
- TRPM7 and Notch vascular signalling: new targets to improve coronary collateral circulation after acute myocardial infarction?
- Neves, Karla (Principal Investigator)
- 01-Jan-2024 - 30-Jan-2027
- Cardiovascular effects of the anti-cancer combination therapy with VEGF inhibitors and immune checkpoint inhibitors
- Neves, Karla (Principal Investigator)
- 01-Jan-2023 - 28-Jan-2024
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Contact
Dr
Karla
Neves
Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: karla.neves@strath.ac.uk
Tel: 548 3430