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Dr Alison Nordon

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Pure and Applied Chemistry

Publications

In-situ ultrasonic imaging of dynamic process streams : system calibration and image processing
Ingram Marcus, Nordon Alison, Gachagan Anthony, Mulholland Anthony, Mineo Carmelo, Becker Edo
SciX Conference 2017, (2017)
Crystallization diagram for antisolvent crystallization of lactose : using design of experiments to investigate continuous mixing- induced supersaturation
Macfhionnghaile Pól, Svoboda Vaclav, McGinty John, Nordon Alison, Sefcik Jan
Crystal Growth and Design Vol 17, pp. 2611-2621, (2017)
http://dx.doi.org/10.1021/acs.cgd.7b00136
Spray drying as a reliable route to produce metastable carbamazepine form IV
Halliwell Rebecca A., Bhardwaj Rajni M., Brown Cameron, Briggs Naomi E. B., Dunn Jaclyn, Robertson John, Nordon Alison, Florence Alastair J.
Journal of Pharmaceutical Sciences Vol 106, pp. 1874-1880, (2017)
http://dx.doi.org/10.1016/j.xphs.2017.03.045
Multivariate data analysis and metabolic profiling of artemisinin and related compounds in high yielding varieties of Artemisia annua field-grown in Madagascar
Suberu John, Gromski Piotr S., Nordon Alison, Lapkin Alexei
Pharmaceutical and Biomedical Sciences: an International Journal Vol 117, pp. 522-531, (2016)
http://dx.doi.org/10.1016/j.jpba.2015.10.003
System modeling and device development for passive acoustic monitoring of a particulate-liquid process
Tramontana Manuel, Gachagan Anthony, Nordon Alison, Littlejohn David, O'Leary Richard, Mulholland Anthony J.
Sensors and Actuators A: Physical Vol 228, pp. 159-169, (2015)
http://dx.doi.org/10.1016/j.sna.2015.03.022
Estimation of particle size distribution and aspect ratio of non-spherical particles from chord length distribution
Agimelen Okpeafoh S., Hamilton Peter, Haley Ian, Nordon Alison, Vasile Massimiliano, Sefcik Jan, Mulholland Anthony J.
Chemical Engineering Science Vol 123, pp. 629-640, (2015)
http://dx.doi.org/10.1016/j.ces.2014.11.014

more publications

Professional activities

EuroPACT 2014
Participant
6/5/2014
PhD examiner
External Examiner
3/4/2014
Royal Society International Scientific Seminar on Nanomaterials by Design
Invited speaker
2/3/2014
2nd Nordic Conference on Vibrational Spectroscopy
Invited speaker
21/10/2013
SciX 2013
Speaker
29/9/2013
IRDG meeting Sept 2013
Invited speaker
13/9/2013

more professional activities

Projects

Doctoral Training Centre In Continuous Manufacturing And Crystallisation | Lothian, Joanna Louise
Nordon, Alison (Principal Investigator) Littlejohn, David (Co-investigator)
Period 01-Apr-2013 - 01-Feb-2018
Industrial Case Account 2014 | Ingram, Marcus
Gachagan, Anthony (Principal Investigator) Nordon, Alison (Co-investigator) Ingram, Marcus (Research Co-investigator)
Period 01-Oct-2015 - 01-Apr-2019
Industrial support for EPSRC ICASE Award for Advanced Ultrasonic Array Imaging | Ingram, Marcus
Gachagan, Anthony (Principal Investigator) Nordon, Alison (Co-investigator) Ingram, Marcus (Research Co-investigator)
Period 01-Oct-2015 - 01-Apr-2019
ModLife
Sahin, Atakan (Researcher) Mishra, Puneet (Researcher) Nordon, Alison (Co-investigator) Morris, Anthony (Co-investigator) Pan, Jiazhu (Co-investigator)
ModLife is a strong European network consisting of 5 leading universities as academic partners and 4 major companies and 2 SMEs as industrial partners joining forces to realize the vision and the objectives of this initiative. The network represents in total 5 European countries. The network undertakes innovative and original research and offers scientific training in Model-based Optimization, Monitoring and Control as Enabling Technologies for process/product development and innovation in life science industries. ModLife provides unique multi-sectoral and multi-disciplinary research and training opportunities for a total of 15 ESRs with an equivalent of 540 months with background in chemistry, biology, physics, applied mathematics and statistics, optimization and control, chemical and process engineering. The interdisciplinary skills developed by the network are urgently required by the life science industrial sectors. It will also open new employment opportunities in virtually every sector of life science industries including healthcare, biotechnology, food production, etc.
Period 01-Jan-2016 - 31-Dec-2019
Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)
Florence, Alastair (Principal Investigator) Halbert, Gavin (Co-investigator) Johnston, Blair (Co-investigator) Nordon, Alison (Co-investigator) Price, Chris John (Co-investigator) Sefcik, Jan (Co-investigator) Ter Horst, Joop (Co-investigator)
"Our Hub research is driven by the societal need to produce medicines and materials for modern living through novel manufacturing processes. The enormous value of the industries manufacturing these high value products is estimated to generate £50 billion p.a. in the UK economy. To ensure international competitiveness for this huge UK industry we must urgently create new approaches for the rapid design of these systems, controlling how molecules self-assemble into small crystals, in order to best formulate and deliver these for patient and customer. We must also develop the engineering tools, process operations and control methods to manufacture these products in a resource-efficient way, while delivering the highest quality materials. Changing the way in which these materials are made, from what is called batch crystallisation (using large volume tanks) to continuous crystallisation (a more dynamic, flowing process), gives many advantages, including smaller facilities, more efficient use of expensive ingredients such as solvents, reducing energy requirements, capital investment, working capital, minimising risk and variation and, crucially, improving control over the quality and performance of the particles making them more suitable for formulation into final products. The vision is to quickly and reliably design a process to manufacture a given material into the ideal particle using an efficient continuous process, and ensure its effective delivery to the consumer. This will bring precision medicines and other highly customisable projects to market more quickly. An exemplar is the hubs exciting innovation partnership with Cancer Research UK. Our research will develop robust design procedures for rapid development of new particulate products and innovative processes, integrate crystallisation and formulation to eliminate processing steps and develop reconfiguration strategies for flexible production. This will accelerate innovation towards redistributed anufacturing, more personalisation of products, and manufacturing closer to the patient/customer. We will develop a modular MicroFactory for integrated particle engineering, coupled with a fully integrated, computer-modelling approach to guide the design of processes and materials at molecule, particle and formulation levels. This will help optimise what we call the patient-centric supply chain and provide customisable products. We will make greater use of targeted experimental design, prediction and advanced computer simulation of new formulated materials, to control and optimise the processes to manufacture them. Our talented team of scientists will use the outstanding capabilities in the award winning £34m CMAC National Facility at Strathclyde and across our 6 leading university spokes (Bath, Cambridge, Imperial, Leeds, Loughborough, Sheffield). This builds on existing foundations independently recognised by global industry as 'exemplary collaboration between industry, academia and government which represents the future of pharmaceutical manufacturing and supply chain framework'. Our vision will be translated from research into industry through partnership and co-investment of £31m. This includes 10 of world's largest pharmaceutical companies (eg AstraZeneca, GSK), chemicals and food companies (Syngenta, Croda, Mars) and 19 key technology companies (Siemens, 15 SMEs) Together, with innovation spokes eg Catapult (CPI) we aim to provide the UK with the most advanced, integrated capabilities to deliver continuous manufacture, leading to better materials, better value, more sustainable and flexible processes and better health and well-being for the people of the UK and worldwide. CMAC will create future competitive advantage for the UK in medicines manufacturing and chemicals sector and is strongly supported by industry / government bodies, positioning the UK as the investment location choice for future investments in research and manufacturing."
Period 01-Jan-2017 - 31-Dec-2023
Collaborative Training Account | WILSDON, David
Nordon, Alison (Principal Investigator) WILSDON, David (Research Co-investigator)
Period 01-Nov-2008 - 23-May-2013

more projects

Address

Pure and Applied Chemistry
Royal College Building

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