Dr David Palmer


Pure and Applied Chemistry


Personal statement

I am a Reader in Chemistry at the University of Stratchlyde.  I was born in London, but grew up in Cumbria in north west England.  After obtaining a Masters degree in Chemistry from the University of Sheffield, I worked as a synthesis chemist for Norbrook Laboratories before reading my PhD in Chemistry at the University of Cambridge.  Between 2008 and 2011, I was a postdoctoral researcher at Aarhus University in Denmark and then at the Max Planck Institute for Mathematics in the Sciences in Leipzig, Germany.   In 2012 I was awarded a Marie Curie Research Fellowship and returned to the UK to join the Department of Physics at the University of Strathclyde.  I started as a Lecturer in the Department of Pure and Applied Chemistry in 2014.   I was promoted to Senior Lecturer in 2019, and to Reader in 2022.

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Area of Expertise

  • Theoretical and computational chemistry
  • Solvation Thermodynamics
  • Molecular Simulation
  • Cheminformatics/Bioinformatics
  • Drug Discovery
  • Biochemistry
  • Machine Learning

Prize And Awards

Chemical Structures Association Trust Grant
Marie Curie Intra-European Fellowship (FP7-PEOPLE-2010-IEF - 272391 - IETSOL)

More prizes and awards

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bbSelect : an open-source tool for performing a 3D pharmacophore-driven diverse selection of R-groups
Rianjongdee Francesco, Palmer David, Pickett Stephen D, Pogány Peter, Tomkinson Nicholas CO, Green Darren VS
Journal of Chemical Information and Modeling (2024)
Bioprocess monitoring applications of an innovative ATR-FTIR spectroscopy platform
Christie Loren, Rutherford Samantha, Palmer David S, Baker Matthew J, Butler Holly J
Frontiers in Bioengineering and Biotechnology Vol 12 (2024)
Rapid detection of heart failure using a spectroscopic liquid biopsy
Christie Loren, Sala Alexandra, Cameron James M, Conn Justin JA, Palmer David S, McGeown William J, Cannon Jane A, Sharp John, Baker Matthew J
Clinical Spectroscopy Vol 5 (2023)
Structure-guided design of a domain-selective bromodomain and extra terminal N-terminal bromodomain chemical probe
Bradley Erin, Fusani Lucia, Chung Chun-wa, Craggs Peter D, Demont Emmanuel H, Humphreys Philip G, Mitchell Darren J, Phillipou Alexander, Rioja Inmaculada, Shah Rishi R, Wellaway Christopher R, Prinjha Rab K, Palmer David S, Kerr William J, Reid Marc, Wall Ian D, Cookson Rosa
Journal of Medicinal Chemistry Vol 66, pp. 15728-15749 (2023)
Global serum profiling an opportunity for earlier cancer detection
Sala Alexandra, Cameron James M, Brennan Paul M, Crosbie Emma J, Curran Tom, Gray Ewan, Martin-Hirsch Pierre, Palmer David S, Rehman Ihtesham U, Rattray Nicholas J W, Baker Matthew J
Journal of Experimental & Clinical Cancer Research Vol 42 (2023)
Augmentation of FTIR spectral datasets using Wasserstein generative adversarial networks for cancer liquid biopsies
McHardy Rose G, Antoniou Georgios, Conn Justin J A, Baker Matthew J, Palmer David S
Analyst Vol 148, pp. 3860-3869 (2023)

More publications

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Research Interests

The main focus of my research is the development and application of molecular simulation and molecular informatics methods to solve industrially relevant problems at the interface between biochemistry and chemical physics.  Recent examples have included the development of new methods for computational drug discovery (in collaboration with AstraZeneca, GSK, and Pfizer) and the design of an enzyme for use in food manufacturing (in collaboration with Chr. Hansen A/S).   I am Founding Director of the cancer diagnostics company, Dxcover (formerly ClinSpec Diagnostics Ltd)

Professional Activities

Spectroscopic Liquid Biopsies to Detect Cancer
Computational Chemistry Research in the Strathclyde Computational and Theoretical Chemistry Hub
Solubility Prediction: A Problem with a Solution?
Simultaneous Entropy, Enthalpy and Free Energy Prediction using a Physics-Informed Neural Network and Multi-task Learning
Cancer Detection using an AI-Enabled Spectroscopic Liquid Biopsy
Simultaneous Entropy, Enthalpy and Free Energy Prediction using a Physics-Informed Neural Network and Multi-task Learning

More professional activities


DTP 2224 University of Strathclyde | Falloon, Kierran
Henrich, Oliver (Principal Investigator) Palmer, David (Co-investigator) Falloon, Kierran (Research Co-investigator)
01-Jan-2023 - 01-Jan-2027
Afon Technology. Short Project
Palmer, David (Principal Investigator)
01-Jan-2023 - 31-Jan-2023
DTP 2224 University of Strathclyde | Fyfe, Calum
Reid, Marc (Principal Investigator) Palmer, David (Co-investigator) Fyfe, Calum (Research Co-investigator)
01-Jan-2022 - 01-Jan-2027
Doctoral Training Partnership 2020-2021 University of Strathclyde | Taylor, Madeleine
Palmer, David (Principal Investigator) Reid, Marc (Co-investigator) Taylor, Madeleine (Research Co-investigator)
01-Jan-2021 - 01-Jan-2025
Development of molecular-solvent interaction descriptors to improve accuracy of Quantitative Structure Retention Relationship model
Palmer, David (Principal Investigator)
01-Jan-2021 - 31-Jan-2025
Solvation thermodynamics of non-aqueous solvent in the 3D Reference Interaction Site Model (3D-RISM).
Palmer, David (Principal Investigator)
256000 CPU hours awarded on Cirrus (EPSRC Tier-2 National HPC Facility at University of Edinburgh)
27-Jan-2021 - 27-Jan-2022

More projects

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Dr David Palmer
Pure and Applied Chemistry

Email: david.palmer@strath.ac.uk
Tel: 548 4178