Dr David Palmer
Reader
Pure and Applied Chemistry
Personal statement
I am a Reader in Chemistry at the University of Stratchlyde. I was born in London, but grew up in Cumbria in north west England. After obtaining a Masters degree in Chemistry from the University of Sheffield, I worked as a synthesis chemist for Norbrook Laboratories before reading my PhD in Chemistry at the University of Cambridge. Between 2008 and 2011, I was a postdoctoral researcher at Aarhus University in Denmark and then at the Max Planck Institute for Mathematics in the Sciences in Leipzig, Germany. In 2012 I was awarded a Marie Curie Research Fellowship and returned to the UK to join the Department of Physics at the University of Strathclyde. I started as a Lecturer in the Department of Pure and Applied Chemistry in 2014. I was promoted to Senior Lecturer in 2019, and to Reader in 2022.
Area of Expertise
- Theoretical and computational chemistry
- Solvation Thermodynamics
- Molecular Simulation
- Cheminformatics/Bioinformatics
- Drug Discovery
- Biochemistry
- Machine Learning
Prize And Awards
- Trustee
- Recipient
- 1/1/2016
- Chemical Structures Association Trust Grant
- Recipient
- 2/6/2014
- Marie Curie Intra-European Fellowship (FP7-PEOPLE-2010-IEF - 272391 - IETSOL)
- Recipient
- 1/2/2012
Publications
- bbSelect : an open-source tool for performing a 3D pharmacophore-driven diverse selection of R-groups
- Rianjongdee Francesco, Palmer David, Pickett Stephen D, Pogány Peter, Tomkinson Nicholas CO, Green Darren VS
- Journal of Chemical Information and Modeling Vol 64, pp. 4687-4699 (2024)
- https://doi.org/10.1021/acs.jcim.4c00453
- Bioprocess monitoring applications of an innovative ATR-FTIR spectroscopy platform
- Christie Loren, Rutherford Samantha, Palmer David S, Baker Matthew J, Butler Holly J
- Frontiers in Bioengineering and Biotechnology Vol 12 (2024)
- https://doi.org/10.3389/fbioe.2024.1349473
- CREATE-2 : Colorectal cancer & adenoma test evaluation of a multi-omic blood test
- Cameron James M, Antoniou Georgios, McHardy Rose, Palmer David, Sala Alexandra, Baker Matthew
- Cancer Research Vol 84 (2024)
- https://doi.org/10.1158/1538-7445.AM2024-7294
- Rapid detection of heart failure using a spectroscopic liquid biopsy
- Christie Loren, Sala Alexandra, Cameron James M, Conn Justin JA, Palmer David S, McGeown William J, Cannon Jane A, Sharp John, Baker Matthew J
- Clinical Spectroscopy Vol 5 (2023)
- https://doi.org/10.1016/j.clispe.2023.100029
- Structure-guided design of a domain-selective bromodomain and extra terminal N-terminal bromodomain chemical probe
- Bradley Erin, Fusani Lucia, Chung Chun-wa, Craggs Peter D, Demont Emmanuel H, Humphreys Philip G, Mitchell Darren J, Phillipou Alexander, Rioja Inmaculada, Shah Rishi R, Wellaway Christopher R, Prinjha Rab K, Palmer David S, Kerr William J, Reid Marc, Wall Ian D, Cookson Rosa
- Journal of Medicinal Chemistry Vol 66, pp. 15728-15749 (2023)
- https://doi.org/10.1021/acs.jmedchem.3c00906
- 583P A rapid blood test for the earlier detection of colorectal cancer
- Nobes J, Cameron JM, Sala A, Antoniou Georgios, Conn J J A, McHardy Rose, Palmer David, Baker Matthew J
- Annals of Oncology Vol 34 (2023)
- https://doi.org/10.1016/j.annonc.2023.09.1774
Research Interests
The main focus of my research is the development and application of molecular simulation and molecular informatics methods to solve industrially relevant problems at the interface between biochemistry and chemical physics. Recent examples have included the development of new methods for computational drug discovery (in collaboration with AstraZeneca, GSK, and Pfizer) and the design of an enzyme for use in food manufacturing (in collaboration with Chr. Hansen A/S). I am Founding Director of the cancer diagnostics company, Dxcover (formerly ClinSpec Diagnostics Ltd)
Professional Activities
- Spectroscopic Liquid Biopsies for the Early Detection of Cancer
- Speaker
- 14/5/2025
- Development of Solvation-Based Molecular Descriptors for Predicting Physicochemical Properties and Chromatographic Retention Times
- Speaker
- 30/9/2024
- Strathclyde Computational and Theoretical Chemistry Hub
- Speaker
- 3/9/2024
- Beyond Traditional Peptide Design: Exploring Peptoid and Aliphatic Molecular Assembly
- Examiner
- 16/5/2024
- Spectroscopic liquid biopsies for the early detection of brain tumours
- Speaker
- 10/5/2024
- Application of ATR-FTIR spectroscopy for the direct detection of stimulants in biofluids
- Examiner
- 18/4/2024
Projects
- DTP 2224 University of Strathclyde | Falloon, Kierran
- Henrich, Oliver (Principal Investigator) Palmer, David (Co-investigator) Falloon, Kierran (Research Co-investigator)
- 01-Oct-2023 - 01-Apr-2027
- Afon Technology. Short Project
- Palmer, David (Principal Investigator)
- 01-May-2023 - 31-Jul-2023
- DTP 2224 University of Strathclyde | Fyfe, Calum
- Reid, Marc (Principal Investigator) Palmer, David (Co-investigator) Fyfe, Calum (Research Co-investigator)
- 01-Oct-2022 - 01-Apr-2027
- Doctoral Training Partnership 2020-2021 University of Strathclyde | Taylor, Madeleine
- Palmer, David (Principal Investigator) Reid, Marc (Co-investigator) Taylor, Madeleine (Research Co-investigator)
- 01-Oct-2021 - 01-Apr-2025
- Development of molecular-solvent interaction descriptors to improve accuracy of Quantitative Structure Retention Relationship model
- Palmer, David (Principal Investigator)
- 01-Oct-2021 - 31-Mar-2025
- Solvation thermodynamics of non-aqueous solvent in the 3D Reference Interaction Site Model (3D-RISM).
- Palmer, David (Principal Investigator)
- 256000 CPU hours awarded on Cirrus (EPSRC Tier-2 National HPC Facility at University of Edinburgh)
- 27-Sep-2021 - 27-Sep-2022
Contact
Dr
David
Palmer
Reader
Pure and Applied Chemistry
Email: david.palmer@strath.ac.uk
Tel: 548 4178