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Dr Brian Patton

Strathclyde Chancellor'S Fellow


Personal statement

My research interests lie in exploiting properties of diamond that allow it to sense electric and magnetic fields. By optically imaging sub-100nm particles of diamond, I hope to use them as sensors for detecting the fields generated by living cells, particularly neurons.

In order to take advantage of the small size of the nanodiamond, I also use superresolution techniques to increase the precision with which we can determine the location of the nanodiamond. As the particles are embedded in living tissue, it will also be necessary to use adaptive optics methods to correct for the optical aberrations introduced by the tissue and which, uncorrected, would degrade the quality of the imaging.


Three-dimensional STED microscopy of aberrating tissue using dual adaptive optics
Patton Brian R., Burke Daniel, Owald David, Gould Travis J., Bewersdorf Joerg, Booth Martin J.
AMB Express Vol 24, pp. 8862-8876, (2016)
All-optical method for characterizing individual fluorescent nanodiamonds
Miles Benjamin T., Greenwood Alexander B., Patton Brian R., Gersen Henkjan
ACS Photonics Vol 3, pp. 343-348, (2016)
Adaptive optics for single molecule switching nanoscopy
Burke Daniel, Patton Brian, Huang Fang, Bewersdorf Joerg, Booth Martin J.
2015 Conference on Lasers and Electro-Optics, CLEO 2015, pp. 2267, (2015)
Is phase-mask alignment aberrating your STED microscope?
Patton Brian R., Burke Daniel, Vrees Robert, Booth Martin J.
Methods and Applications in Fluorescence Vol 3, (2015)
Adaptive optics correction of specimen-induced aberrations in single-molecule switching microscopy
Burke Daniel, Patton Brian, Huang Fang, Bewersdorf Joerg, Booth Martin J.
Optica Vol 2, pp. 177-185, (2015)
Adaptive Optics for Fluorescence Microscopy
Booth Martin J., Patton Brian R.
Fluorescence MicroscopyFluorescence Microscopy, (2014)

more publications

Professional activities

Institute of Physics (External organisation)
Royal Society - My Experiences as a University Research Fellow
Brexit research and Innovation Futures Workshop
Royal Society Industry Fellows Networking Event
Royal Society Meeting of Minds
Invited speaker for Physics and Life Sciences Theme
Invited speaker

more professional activities


Multiscale neural imaging - from synapse to whole-organism
Patton, Brian (Principal Investigator)
Period 01-Dec-2017 - 31-Mar-2021
Low-cost, open-access imaging for identifying and quantifying water quality (GCRF)
Patton, Brian (Principal Investigator)
Period 04-Dec-2017 - 03-Dec-2018
Nanodiamond as an optically robust fluorophore for targeted imaging of neural structures
Patton, Brian (Principal Investigator)
This is a studentship awarded under the Diamond Sciences and Technologies Centre for Doctoral Training, headed by the University of Warwick.
Period 01-Sep-2017 - 01-Sep-2021
Super-resolution microscopy for clinical research: Detecting mitochondrial interactions with intracellular bacteria after bacterial challenge.
Patton, Brian (Principal Investigator)
This is an Optima Centre for Doctoral Training-funded PhD studentship.
Period 01-Sep-2017 - 01-Sep-2021
Direct Wavefront Sensing for Efficient Measurement of Electronic Spin in Nanodiamond
Patton, Brian (Principal Investigator)
Period 15-Mar-2018 - 14-Mar-2019
EPSRC-Royal Society fellowship engagement (2013):Visualising thoughts: ESR measurement of nanodiamonds targetted to neural structures
Patton, Brian (Principal Investigator)
Please refer to attached Royal Society application.
Period 21-Oct-2016 - 30-Nov-2018

more projects