Dr Binoy Paulose Nadappuram
Strathclyde Chancellor's Fellow
Pure and Applied Chemistry
Personal statement
Binoy Paulose Nadappuram is a Lecturer (Assistant Professor) and Chancellor’s Fellow in the Department of Pure and Applied Chemistry. His research focuses on the development of new single molecule manipulation platforms for diagnostic applications and real-time analysis of biological systems with enhanced spatio-temporal resolution.
Binoy obtained his PhD from the University of Warwick, where he developed new electrochemical methods for quantitative visualization ion fluxes at physiochemical and biological interfaces. He then moved to Imperial College London, where he was a research associate and Wellcome Trust ISSF Fellow in the Department of Chemistry. Prior to joining the University of Warwick, Binoy worked as a Research Engineer at the Centre of Innovation in Environment and Water Technology (EWT COI), Singapore.
Publications
- Tracking gene expression of single mitochondria in live neurons using nanotweezers
- Sahota Annie, Paulose Nadappuram Binoy, Allerton Siân C, Lesept Flavie, Howden Jack H, Claxton Suzanne, Liu Yaxian, Aprile Francesco A, Kittler Josef T, Devine Michael J, Ivanov Aleksandar P, Edel Joshua B
- Journal of the American Chemical Society Vol 148, pp. 24863–24874 (2026)
- https://doi.org/10.1021/jacs.6c02802
- Interface-induced concentration enhancement in glycine solutions investigated using surface plasmon resonance spectroscopy and molecular dynamics simulations
- Mackay Ruairidh, Mohammadpour Mozhdeh, Paulose Nadappuram Binoy, Johnston Karen, Sefcik Jan, Lau King Hang Aaron
- The Journal of Physical Chemistry Letters Vol 17, pp. 5535–5540 (2026)
- https://doi.org/10.1021/acs.jpclett.5c03688
- Spatial and temporal single-cell profiling of RNA compartmentalization in neurons with nanotweezers
- Sahota Annie, Paulose Nadappuram Binoy, Kwan Zoe, Lesept Flavie, Howden Jack H, Claxton Suzanne, Kittler Josef T, Devine Michael J, Edel Joshua B, Ivanov Aleksandar P
- ACS Nano Vol 19, pp. 18522-18533 (2025)
- https://doi.org/10.1021/acsnano.5c02056
- Microtubule-mediated regulation of β2AR translation and unction in failing hearts
- Kwan Zoe, Nadappuram Binoy P, Leung Manton M, Kondrashov Alexander, Mohagaonkar Sanika, Li Ao, Amaradasa Kumuthu S, Chen Ji, Rothery Stephen, Kibreab Iyobel, Fu Jiarong, Sanchez-Alonso Jose L, Mansfield Catherine A, Subramanian Hariharan, Wright Peter T, Swiatlowska Pamela, Nikolaev Viacheslav O, Wojciak-Stothard Beata, Ivanov Aleksandar P, Edel Joshua B, Gorelik Julia
- Circulation Research Vol 133, pp. 944–958 (2023)
- https://doi.org/10.1161/circresaha.123.323174
- Recent advances in single-cell subcellular sampling
- Sahota Annie, Monteza Cabrejos Anthony, Kwan Zoe, Paulose Nadappuram Binoy, Ivanov Aleksandar P, Edel Joshua B
- Chemical Communications Vol 59, pp. 5312-5328 (2023)
- https://doi.org/10.1039/D3CC00573A
- Localised solid-state nanopore fabrication via controlled breakdown using on-chip electrodes
- Fried Jasper P, Swett Jacob L, Paulose Nadappuram Binoy, Fedosyuk Aleksandra, Gee Alex, Dyck Ondrej E, Yates James R, Ivanov Aleksander P, Edel Joshua B, Moi Jan A
- Nano Research Vol 15, pp. 9881-9889 (2022)
- https://doi.org/10.1007/s12274-022-4535-8
Projects
- Dynamic Multiomics Profiling of Single-Synapses for Understanding Learning and Memory Formation
- Paulose Nadappuram, Binoy (Principal Investigator)
- 01-Jan-2026 - 31-Jan-2031
- Development of novel dielectrophoretic platforms for point-of-use applications
- Paulose Nadappuram, Binoy (Principal Investigator)
- 01-Jan-2025 - 31-Jan-2029
- UDLA 2527 University of Strathclyde | Taylor, Jordan
- Paulose Nadappuram, Binoy (Principal Investigator) Corrigan, Damion (Co-investigator) Taylor, Jordan (Research Co-investigator)
- 01-Jan-2025 - 01-Jan-2029
- NorthwestBio DTP
- Gomez-Roman, Natividad (Principal Investigator) Paulose Nadappuram, Binoy (Co-investigator)
- 01-Jan-2023 - 30-Jan-2028
- Development of a single cell biopsy platform to study dynamic transcriptional changes in cancer
- Paulose Nadappuram, Binoy (Principal Investigator)
- 15-Jan-2023 - 12-Jan-2027
- Development of Dielectrophoretic Platforms for Amplification Free Detection of Bioanalytes
- Paulose Nadappuram, Binoy (Principal Investigator)
- 17-Jan-2022 - 16-Jan-2023
Contact
Dr
Binoy
Paulose Nadappuram
Strathclyde Chancellor's Fellow
Pure and Applied Chemistry
Email: binoy.paulose@strath.ac.uk
Tel: 444 7345