Dr Thomas Pickles

Project Scientist

Continuous Manufacturing And Crystallisation

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Publications

Automated scale-up crystallisation DataFactory for model-based pharmaceutical process development : a Bayesian case study
Pickles Thomas, Leghrib Youcef, Weisshaar Matt, Gonacharuk Mikhail, Timperman Peter, Doherty Timothy, Ford David D, Moores Jonathan, Florence Alastair J, Brown Cameron J
Digital Discovery (2025)
https://doi.org/10.1039/D4DD00406J
Integration of a model-driven workflow into an industrial pharmaceutical facility : supporting process development of API crystallisation
Pickles Thomas, Svoboda Vaclav, Marziano Ivan, Brown Cameron J, Florence Alastair J
CrystEngComm Vol 26, pp. 4678-4689 (2024)
https://doi.org/10.1039/d4ce00358f
Comparative study on adaptive Bayesian optimization for batch cooling crystallization for slow and fast kinetic regimes
Pickles Thomas, Mustoe Chantal, Brown Cameron J, Florence Alastair J
Crystal Growth and Design Vol 24, pp. 1245-1253 (2024)
https://doi.org/10.1021/acs.cgd.3c01225
Developing a model-driven workflow for the digital design of small-scale batch cooling crystallisation with the antiviral lamivudine
Pickles Thomas, Mustoe Chantal, Boyle Christopher, Cardona Javier, Brown Cameron J, Florence Alastair J
CrystEngComm Vol 26, pp. 822-834 (2024)
https://doi.org/10.1039/D3CE00897E
Autonomous DataFactory : high-throughput screening for large-scale data collection to inform medicine manufacture
Pickles Thomas, Mustoe Chantal, Brown Cameron, Florence Alastair
British Journal of Pharmacy Vol 7 (2022)
https://doi.org/10.5920/bjpharm.1128
Towards an autonomous DataFactory for the small-batch cooling crystallisation of active pharmaceutical ingredients
Mustoe Chantal, Pickles Thomas, Brown Cameron, Florence Alastair
CMAC Annual Open Day 2022, pp. 66-66 (2022)

More publications

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Contact

Dr Thomas Pickles
Project Scientist
Continuous Manufacturing And Crystallisation

Email: thomas.pickles@strath.ac.uk
Tel: Unlisted