Dr Nicholas Rattray
Professor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Personal statement
Principle research interests lie in investigating metabolic changes throughout human life course with a focus on the dynamics of energy metabolism alongside biomarker detection. Currently developing a targeted research theme that incorporates pregnancy, frailty and ageing related clinical projects alongside novel analytical approaches that enable the targeting and quantification of pathways critical to biochemical energy production. Portfolio of clinical research has covered a broad range of concepts including: Population level analysis of frailty metabolism Early diagnostic and theranostic biomarker detection Energy metabolism across the placenta Ageing effects the biological and metabolic basis of cancer This work has also been complemented by development of statistical tools to understand how metabolite data can be automatically linked to biochemical pathways, helping to inform genomic studies and ultimately to develop models linking metabolic data and exposures to epidemiological studies. Expertise & Capabilities Lab has broad experience in: Development of cellular models of disease and ageing Technical application of untargeted and targeted mass spectrometry based metabolomics pipelines with a view to high through-put levels of analysis Automation of pre/post processing and informatics Development of imaging mass spectrometry capability Enabling of a broad range of targeted MS workflow focusing on energy metabolites
Area of Expertise
Lab has broad experience in
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Publications
- Later life precarity and longitudinal frailty trajectories in older adults
- Rowley-Abel Laurence, van den Driest Lisa, Chen Qingwen, Chen Yulu, Chu Su, Lasky-Su Jessica, Rattray Nicholas JW, Marshall Alan
- Ageing and Society Vol 46 (2026)
- https://doi.org/10.1017/S0144686X26100543
- The application of omics technologies in Type II diabetes mellitus research
- Al Sultan Abdullah, Rattray Zahra, Rattray Nicholas J W
- Current Diabetes Reviews Vol 22 (2026)
- https://doi.org/10.2174/0115733998362669250424162654
- OMICmAge quantifies biological age by integrating multi-omics with electronic medical records
- Chen Qingwen, Dwaraka Varun B, Carreras-Gallo Natàlia, Armstrong Jenel F, Sehgal Raghav, Argentieri M Austin, Richmond Anne, Aparicio Andrea, Mendez Kevin, Chen Yulu, Begum Sofina, Kachroo Priyadarshini, Prince Nicole, Guo Tao, Went Hannah, Mendez Tavis, Lin Aaron, Turner Logan, Moqri Mahdi, Chu Su H, Kelly Rachel S, Weiss Scott T, Rattray Nicholas J W, Gladyshev Vadim N, Karlson Elizabeth, Wheelock Craig E, Mathé Ewy A, Dahlin Amber, McGeachie Michael J, Marioni Riccardo E, Higgins-Chen Albert T, Smith Ryan, Lasky-Su Jessica
- Nature Aging Vol 6, pp. 722-737 (2026)
- https://doi.org/10.1038/s43587-026-01073-7
- Multi-detector frit-inlet asymmetric flow field-flow fractionation method development for nanoparticle mixtures : deeper analysis beyond ISO quality standards
- Abdulrahman Rand, Punnabhum Panida, Van Den Driest Lisa, Rattray Nicholas J W, Capomaccio Robin, Treacher Kevin, Perrie Yvonne, Rattray Zahra
- Analytical Methods Vol 18, pp. 1637-1653 (2026)
- https://doi.org/10.1039/D5AY01758K
- Does modified 5-item frailty index correlate with survival in oropharyngeal squamous cell carcinoma?
- Chmielecka Marta, Hurley Rhona, Slim Mohd Afid Mohd, Philp Nichola, Donachie Matthew, Horackiewicz Jan, McGovern Josh, Knight Katrina, Rattray Nicholas J W, Paterson Claire, Douglas Catriona M
- Head and Neck Vol 48, pp. 82-98 (2026)
- https://doi.org/10.1002/hed.70005
- Colorectal cancer molecular profiling : opportunities for early detection
- Sala Alexandra, van den Driest Lisa, Rattray Nicholas J W, Johnson Caroline H, Cameron James M, Khan Sajid A, Palmer David S, Baker Matthew J
- Clinical and Translational Medicine Vol 15 (2025)
- https://doi.org/10.1002/ctm2.70474
Professional Activities
- Overview of Metabolomics in Scotland
- Speaker
- 26/11/2026
- Frailty sets in far earlier than you'd expect, but you can reverse it.
- Recipient
- 9/3/2026
- Modeling the ageing metabolome.
- Speaker
- 13/1/2026
- Kaiyun Chen
- Host
- 12/2025
- Genomics meets exposomics: advancing gene by environment science
- Participant
- 20/10/2025
- Cancer Research UK CRUK (External organisation)
- Advisor
- 25/9/2025
Projects
- ACORN: Assessment of Chronic Opioid Risk using Neurobiology
- Rattray, Nicholas (Principal Investigator)
- 01-Jan-2025 - 31-Jan-2027
- DTP 2224 University of Strathclyde | Almawazini, Mohammad
- Rattray, Nicholas (Principal Investigator) Rattray, Zahra (Co-investigator) Almawazini, Mohammad (Research Co-investigator)
- 01-Jan-2025 - 01-Jan-2028
- CAMS Industry Partnership
- Rattray, Nicholas (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2027
- Frailty (eFI JARSS NHS Monies)
- Rattray, Nicholas (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2028
- Dxcover Brain Cancer Analysis
- Rattray, Nicholas (Principal Investigator) Rattray, Zahra (Co-investigator)
- 01-Jan-2024 - 30-Jan-2025
- Dementia biomarker detection using resonant Raman spectroscopy at point of need.
- Rattray, Nicholas (Principal Investigator)
- 01-Jan-2024 - 31-Jan-2025
Contact
Dr
Nicholas
Rattray
Professor
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: nicholas.rattray@strath.ac.uk
Tel: 548 2012