Personal statement
Principle research interests lie in investigating metabolic changes throughout human life course with a focus on the dynamics of energy metabolism alongside biomarker detection. Currently developing a targeted research theme that incorporates pregnancy, frailty and ageing related clinical projects alongside novel analytical approaches that enable the targeting and quantification of pathways critical to biochemical energy production.
Portfolio of clinical research has covered a broad range of concepts including:
Population level analysis of frailty metabolism
Early diagnostic and theranostic biomarker detection
Energy metabolism across the placenta
Ageing effects the biological and metabolic basis of cancer
This work has also been complemented by development of statistical tools to understand how metabolite data can be automatically linked to biochemical pathways, helping to inform genomic studies and ultimately to develop models linking metabolic data and exposures to epidemiological studies.
Expertise & Capabilities
Lab has broad experience in:
Development of cellular models of disease and ageing
Technical application of untargeted and targeted mass spectrometry based metabolomics pipelines with a view to high through-put levels of analysis
Automation of pre/post processing and informatics
Development of imaging mass spectrometry capability
Enabling of a broad range of targeted MS workflow focusing on energy metabolites
Professional activities
- Using storytelling to recount the untold narratives of breast cancer
- Contributor
- 15/12/2022
- Breaking Barriers
- Speaker
- 20/9/2022
- British Mass Spectrometry Society Annual Conference
- Participant
- 14/9/2022
- Invited Vendor (Shimadzu UK) Talk on Translating biological models of the ageing metabolome in to clinically relevant biomarkers.
- Speaker
- 14/9/2022
- External Viva examiner
- Examiner
- 6/9/2022
- Recounting the Untold Stories of Breast Cancer: Narratives from the Patient, Clinician and Scientist Perspective
- Contributor
- 2/8/2022
More professional activities
Projects
- Innovation in rehabilitation technologies through multimodal blood analysis
- Jimenez, Melanie (Principal Investigator) Kerr, Andy (Co-investigator) Rattray, Nicholas (Co-investigator)
- 27-Jan-2023 - 26-Jan-2024
- A pilot study evaluating the correlation between RA disease activity and gut dysbiosis
- Rattray, Nicholas (Principal Investigator) Rattray, Zahra (Co-investigator)
- 01-Jan-2023 - 31-Jan-2024
- DTP 2224 University of Strathclyde | Van Den Driest, Lisa
- Rattray, Nicholas (Principal Investigator) Rattray, Zahra (Co-investigator) Van Den Driest, Lisa (Research Co-investigator)
- 01-Jan-2022 - 01-Jan-2026
- To develop a genome-based data mining approach to stratification in breast cancer Copy
- Rattray, Nicholas (Principal Investigator)
- 13-Jan-2022 - 05-Jan-2022
- Recounting the Untold Stories of Breast Cancer: Narratives from the Patient, Clinician and Scientist Perspective
- Rattray, Zahra (Principal Investigator) Rattray, Nicholas (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Chalmers, Susan (Co-investigator) MCFADDEN, Yvonne (Co-investigator)
- £5700 awarded to develop a series of storytelling events
- 14-Jan-2022 - 13-Jan-2023
- A novel dietary therapy to control recurrence of gut inflammation in children with Crohn’s disease in remission
- Rattray, Nicholas (Principal Investigator)
- 01-Jan-2021 - 01-Jan-2025
More projects
Address
Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing
Robertson Wing
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