Dr Zahra Rattray
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Area of Expertise
Expertise
I am an interdisciplinary pharmaceutical researcher with experience in developing injectable drugs (antibodies, small molecules, and nanomedicines). I have significant expertise in the analytical characterization of critical quality attributes for these products and the design of pre-clinical studies for evaluating biological performance (biopharmaceutics).
Equipment Capabilities
My laboratory hosts a Malvern Panalytical NanoSight NS300 and Archimedes Resonant Mass Measurement, which are both used to measure particle size and concentration. If you would be interested in accessing these technologies, please get in touch (zahra.rattray@strath.ac.uk).
I am also Director for the new EPSRC Multiscale Metrology Suite (modular setup including Field Flow Fractionation, Inductively-coupled mass spectrometry, Light Scattering and Raman) for Next-Generation Health Nanotechnologies (EP/V028960/1). For more information or to access this facility, please get in touch.
Prize And Awards
- Academy of Pharmaceutical Sciences Emerging Scientist Award
- Recipient
- 7/9/2023
- Saltire Society’s inaugural 40 Under 40 List
- Recipient
- 22/6/2023
- Sir Robin MacLellan Award
- Recipient
- 19/6/2023
- Women In Leadership Network+
- Recipient
- 9/3/2023
- Fellow of the Academy of Pharmaceutical Sciences of Great Britain
- Recipient
- 7/2022
- International Pharmaceutical Federation Women in Science and Education Rising Star 2022 (FIPWise 2022)
- Recipient
- 30/6/2022
Publications
- Sex differences in colon cancer metabolism reveal a novel subphenotype
- Cai Yuping, Rattray Nicholas J W, Zhang Qian, Mironova Varvara, Santos-Neto Alvaro, Hsu Kuo-Shun, Rattray Zahra, Cross Justin R, Zhang Yawei, Paty Philip B, Khan Sajid A, Johnson Caroline H
- Scientific Reports Vol 10 (2020)
- https://doi.org/10.1038/s41598-020-61851-0
- ENT2 facilitates brain endothelial cell penetration and blood-brain barrier transport by a tumor-targeting anti-DNA autoantibody
- Rattray Zahra, Deng Gang, Zhang Shenqi, Shirali Anupama, May Christopher K, Chen Xiaoyong, Cuffari Benedette J, Liu Jun, Zou Pan, Rattray Nicholas JW, Johnson Caroline H, Dubljevic Valentina, Campbell James A, Huttner Anita, Baehring Joachim M, Zhou Jiangbing, Hansen James E
- JCI Insight Vol 6 (2021)
- https://doi.org/10.1172/jci.insight.145875
- Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
- Rattray Nicholas JW, Trivedi Drupad K, Xu Yun, Chandola Tarani, Johnson Caroline H, Marshall Alan D, Mekli Krisztina, Rattray Zahra, Tampubolon Gindo, Vanhoutte Bram, White Iain R, Wu Frederick CW, Pendleton Neil, Nazroo James, Goodacre Royston
- Nature Communications Vol 10 (2019)
- https://doi.org/10.1038/s41467-019-12716-2
- Evaluation of temporal aggregation processes using spatial intensity distribution analysis
- Rattray Zahra, Zindy Egor, Buzza Karen M, Pluen Alain
- Protein Self-Assembly Methods and Protocols (2019) (2019)
- https://doi.org/10.1007/978-1-4939-9678-0_11
- Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications
- Rattray Zahra, Dubljevic Valentina, Rattray Nicholas, Greenwood Deanne L, Johnson Caroline H, Campbell James A, Hansen James E
- Biochemical and Biophysical Research Communications Vol 496, pp. 858-864 (2018)
- https://doi.org/10.1016/j.bbrc.2018.01.139
- A DNA-damaging lupus autoantibody synergizes with PARP inhibitors against DNA repair-deficient tumor cells
- Rattray Zahra, Patel Jaymin M, Noble Phillip W, Dubljevic Valentina, Greenwood Deanne L, Campbell James A, Hansen James E
- Cancer Research Vol 78, pp. 2773 (2018)
- https://doi.org/10.1158/1538-7445.AM2018-2773
Professional Activities
- EPSRC Peer Review College (External organisation)
- Member
- 6/7/2021
- Royal Society of Edinburgh's Young Academy of Scotland (External organisation)
- Chair
- 4/2021
- Strathclyde MPharm applicant talk
- Speaker
- 17/4/2024
- European Crucible Podcast
- Recipient
- 3/4/2024
- Invited Lecture Nineva University, Iraq
- Speaker
- 3/4/2024
- Internal examiner
- Examiner
- 7/3/2024
Projects
- A Prosperity Partnership for the Design of Next-Generation Antibody Drug Bioconjugates (Next-Gen ADC)
- Burley, Glenn (Principal Investigator) Jamieson, Craig (Co-investigator) Kerr, William (Co-investigator) Nordon, Alison (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator)
- 15-Jan-2023 - 14-Jan-2028
- Developing new bioanalytical pipelines for early-stage assessment of antibody-drug conjugate developability
- Rattray, Zahra (Principal Investigator) Jamieson, Craig (Co-investigator) Jolliffe, Sophie (Research Co-investigator)
- 02-Jan-2023 - 01-Jan-2027
- Nanoparticle Tracking Analysis Launch- Beta testing
- Rattray, Zahra (Principal Investigator)
- 11-Jan-2023 - 10-Jan-2023
- A pilot study evaluating the correlation between RA disease activity and gut dysbiosis
- Rattray, Nicholas (Principal Investigator) Rattray, Zahra (Co-investigator)
- 01-Jan-2023 - 31-Jan-2024
- Strathclyde CDT: Healthcare Nanotechnologies
- Perrie, Yvonne (Principal Investigator) Rattray, Zahra (Principal Investigator) Hoskins, Clare (Principal Investigator) Faulds, Karen (Principal Investigator) Graham, Duncan (Principal Investigator)
- 01-Jan-2022 - 30-Jan-2025
- Novel analytical pipelines for understanding oligonucleotide-loaded lipid nanoparticle critical quality attributes
- Rattray, Zahra (Principal Investigator) Perrie, Yvonne (Co-investigator)
- 01-Jan-2022 - 31-Jan-2026
Contact
Dr
Zahra
Rattray
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Email: zahra.rattray@strath.ac.uk
Tel: 548 2106