Dr Zahra Rattray

Strathclyde Chancellor's Fellow

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

Chancellor's research fellow and lecturer in Drug Delivery I am interested in the interplay between drugs (small molecule, peptide, and monoclonal antibodies), and their formulation characteristics with biological systems. Understanding this interplay can lead to designing new drugs for targeting various cancer types and help overcome biological barriers to delivering drugs. I utilize a combination of new analytical technologies and multidisciplinary science to drive this understanding. My lab is also interested in applying new technologies to understanding the biological drivers of cancer and SLE. When I am not doing science, I am passionate about outreach and inspiring future scientists.

Publications

Sex differences in colon cancer metabolism reveal a novel subphenotype
Cai Yuping, Rattray Nicholas J W, Zhang Qian, Mironova Varvara, Santos-Neto Alvaro, Hsu Kuo-Shun, Rattray Zahra, Cross Justin R, Zhang Yawei, Paty Philip B, Khan Sajid A, Johnson Caroline H
Scientific Reports Vol 10 (2020)
https://doi.org/10.1038/s41598-020-61851-0
Metabolic dysregulation in vitaminĀ E and carnitine shuttle energy mechanisms associate with human frailty
Rattray Nicholas JW, Trivedi Drupad K, Xu Yun, Chandola Tarani, Johnson Caroline H, Marshall Alan D, Mekli Krisztina, Rattray Zahra, Tampubolon Gindo, Vanhoutte Bram, White Iain R, Wu Frederick CW, Pendleton Neil, Nazroo James, Goodacre Royston
Nature Communications Vol 10 (2019)
https://doi.org/10.1038/s41467-019-12716-2
Evaluation of temporal aggregation processes using spatial intensity distribution analysis
Rattray Zahra, Zindy Egor, Buzza Karen M, Pluen Alain
Protein Self-Assembly Methods and Protocols (2019) (2019)
https://doi.org/10.1007/978-1-4939-9678-0_11
Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications
Rattray Zahra, Dubljevic Valentina, Rattray Nicholas, Greenwood Deanne L, Johnson Caroline H, Campbell James A, Hansen James E
Biochemical and Biophysical Research Communications Vol 496, pp. 858-864 (2018)
https://doi.org/10.1016/j.bbrc.2018.01.139
A DNA-damaging lupus autoantibody synergizes with PARP inhibitors against DNA repair-deficient tumor cells
Rattray Zahra, Patel Jaymin M, Noble Phillip W, Dubljevic Valentina, Greenwood Deanne L, Campbell James A, Hansen James E
Cancer Research Vol 78, pp. 2773 (2018)
https://doi.org/10.1158/1538-7445.AM2018-2773
An ENT2-dependent, cell-penetrating, and DNA-damaging lupus autoantibody crosses the blood-brain barrier to target brain tumors
Rattray Zahra, Deng Gang, Zhang Shenqi, Shirali Anupama, May Christopher, Liu Jun, Zou Pan, Cuffari Benedette, Rattray Nicholas, Johnson Caroline, Dubljevic Valentina, Campbell James, Huttner Anita, Baehring Joachim, Zhou Jiangbing, Hansen James
Neuro-Oncology Advances Vol 2, pp. ii13-ii13 (2020)
https://doi.org/10.1093/noajnl/vdaa073.051

More publications

Professional activities

Cell and Gene Therapy
Speaker
19/5/2021
CELL & GENE THERAPY:from concept to medicinal use
Organiser
1/5/2021
Royal Society of Edinburgh's Young Academy of Scotland (External organisation)
Advisor
4/2021
Im a Scientist, get me out of here
Recipient
1/3/2021
Seminar talk- Size Matters
Speaker
24/2/2021
UKRI (External organisation)
Advisor
22/2/2021

More professional activities

Projects

The impact of KPNA2 overexpression on breast cancer cellular phenotype (RSE Reboot)
Rattray, Zahra (Principal Investigator) Rattray, Nicholas (Co-investigator)
08-Jan-2021 - 07-Jan-2021
Nanoparticle Tracking Analysis
Rattray, Zahra (Principal Investigator)
Malvern Nanoparticle Tracking Analysis for particle size and concentration measurement
16-Jan-2020
Doctoral Training Partnership 2018-19 University of Strathclyde | Daramy, Karim
Rattray, Zahra (Principal Investigator) Perrie, Yvonne (Co-investigator) Daramy, Karim (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Obesity and Neuroinflammation: The Impact of Adipocyte-derived Extracellular Vesicles on Inflammatory Signalling Pathways of Microglia
Colvin, Chiara (Post Grad Student) Gould, Gwyn (Co-investigator) Rattray, Zahra (Co-investigator) Cunningham, Margaret Rose (Principal Investigator)
01-Jan-2020 - 30-Jan-2021
Development and preclinical validation of novel PAR2 inhibitors for the treatment of Osteoarthritis
McIntosh, Kathryn (Principal Investigator) Crilly, Anne (Co-investigator) Jamieson, Craig (Co-investigator) Plevin, Robin (Co-investigator) Rattray, Zahra (Co-investigator)
01-Jan-2020 - 30-Jan-2022
Resonant Mass Measurement (Archimedes)
Rattray, Zahra (Principal Investigator)
ECR EPSRC Equipment Award
02-Jan-2019

More projects

Address

Strathclyde Institute of Pharmacy and Biomedical Sciences
Robertson Wing

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