Dr Mairi Sandison

Senior Lecturer

Biomedical Engineering

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Personal statement

My research focuses on exploiting microsystems engineering approaches (lab-on-a-chip, microfluidics, materials engineering) to create new in vitro models for investigating and controlling cell behaviours. Applications of this work include the development of tools for drug screening and for tissue engineering. My background is highly interdisciplinary, spanning the engineering-life science interface, with expertise in a wide range of cell biology, microfabrication, live-cell imaging and analytical technologies. 

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Publications

Functional, patient-derived 3D tri-culture models of the uterine wall in a microfluidic array
Busch Caroline, Hill Christopher J, Paterson Karla, Mellin Ronan, Zagnoni Michele, Hapangama Dharani K, Sandison Mairi E
Human Reproduction (2024)
https://doi.org/10.1093/humrep/deae214
3D printing of noncytotoxic high-resolution microchannels in Bisphenol-a ethoxylate dimethacrylate tissue-mimicking materials
Domingo-Roca Roger, Gilmour Lauren, Dobre Oana, Sarrigiannidis Stylianos, Sandison Mairi E, O'Leary Richard, Mulvana Helen E
3D Printing and Additive Manufacturing Vol 10, pp. 1101-1109 (2023)
https://doi.org/10.1089/3dp.2021.0235
Microwell arrays for long-term confinement and single-cell tracking of phenotypic heterogeneity in vascular smooth muscle populations
Zagnoni Michele, Smith Ellis, Sandison Mairi
2nd Microphysiological Systems, World Summit, Berlin, 2023 (2023)
Cellular microarrays for assessing single-cell phenotypic changes in vascular cell populations
Smith E, Zagnoni M, Sandison M E
Biomedical Microdevices Vol 25 (2023)
https://doi.org/10.1007/s10544-023-00651-5
Microwell arrays for long-term confinement and single-cell tracking of phenotypic changes in vascular cell populations
Smith Ellis, Zagnoni Michele, Sandison Mairi
MNE2022 (48th International Conference on Micro and Nano Engineering) (2022)
Metal oxide-doped elastomeric materials for amplifying visible light-based antimicrobial activity
McShea Laura, Kambo Harjot S, Maclean Michelle, Sandison Mairi E
Materials Research Express Vol 9 (2022)
https://doi.org/10.1088/2053-1591/ac8641

More publications

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Teaching

I have taught on both the BEng/MEng and MSc courses in Biomedical Engineering and I am currently module coordinator for BE105 (Cell Biology 1) and co-lead on the creation and implementation of new UG teaching laboratory classes.

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Research Interests

Current research projects, involving collaboration with a diverse range of academic and clinical collaborators, include:

  • investigating the phenotypic changes in vascular cells that underlie cardiovascular disease
  • the development of organ-on-a-chip models for chronic gynaecological conditions
  • the development of new methods for monitoring mitochondrial dynamics in neuronal preparations
  • the development of novel materials for antimicrobial applications.

Professional Activities

A Microfluidic Approach to Investigating Vascular Cell Fate at the Single-Cell Level
Contributor
24/3/2022
Adenomyosis-on-a-chip: a 3D endometrial-myometrial microfluidic model
Speaker
17/11/2021
Automated tracking of mitochondrial motility using image processing and epifluorescence microscopy
Contributor
25/11/2020
PhD External Examiner
Examiner
9/8/2019
Microwell Arrays for Monitoring Phenotypic Heterogeneity in Vascular Cell Populations
Speaker
25/9/2018

More professional activities

Projects

EPSRC Centre for Doctoral Training in Prosthetics & Orthotics | Brown, Ruth
Sandison, Mairi (Principal Investigator) Buis, Arjan (Co-investigator) Brown, Ruth (Research Co-investigator)
01-Oct-2022 - 01-Oct-2026
Development of a functional organ-in-lab model of human vascular aging
Wu, Junxi (Principal Investigator) Sandison, Mairi (Co-investigator) McCormick, Christopher (Co-investigator)
01-Oct-2022 - 30-Sep-2025
EPSRC IAA: Acceleration of cytocompatible hydrogel discovery: a feasibility assessment of multiplexing approaches to increase screening throughput
Sandison, Mairi (Co-investigator)
01-Apr-2022 - 31-Mar-2025
Adenomyosis-on-a-chip: a microfluidic 3D model of the endometrial-myometrial junction (EMJ)
Sandison, Mairi (Principal Investigator) Zagnoni, Michele (Co-investigator) Busch, Caroline (Researcher)
06-Apr-2021 - 23-Jun-2021
Rational design of novel microfluidics devices for in vitro evaluation of nanomedicine biological fate
Rattray, Zahra (Principal Investigator) Kazakidi, Asimina (Principal Investigator) Sandison, Mairi (Principal Investigator) Perrie, Yvonne (Principal Investigator)
EPSC STEM Equals feasibility grant, part of the EPSRC Inclusion Matters grant (EP/S012133/1). Award: £5,000
01-Nov-2020 - 31-Jan-2021
Doctoral Training Partnership 2020-2021 University of Strathclyde | Gilmour, Lauren
Mulvana, Helen Elizabeth (Principal Investigator) Sandison, Mairi (Co-investigator) Gilmour, Lauren (Research Co-investigator)
01-Oct-2020 - 01-Jul-2024

More projects

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Contact

Dr Mairi Sandison
Senior Lecturer
Biomedical Engineering

Email: mairi.sandison@strath.ac.uk
Tel: 548 3030