Dr Carsten Schulte
Strathclyde Chancellor's Fellow
Biomedical Engineering
Personal statement
The major interest of my research has always been the amazing interaction of cells with their surrounding microenvironment. Within this framework, my main lines of research aim to understand how the force-based dialogue between the cell and the extracellular matrix affects the mechanobiology, signalling and function of the cell. In particular, I am fascinated by the complex molecular mechanotransductive mechanisms that translate biophysical microenvironmental information (e.g., nanotopography) into cellular responses with drastic morphological and functional changes and how this contributes to (patho)physiological situations, such as cellular differentiation and cancer.
To this end, I implement highly interdisciplinary approaches and combine versatile state-of-the-art techniques from various fields such as cell biology, mechanobiology, advanced imaging, engineering (biomaterials), biophysics, pharmacology, nanotechnology, omics and biochemistry.
Prize And Awards
- Strathclyde Chancellor's Fellow
- Recipient
- 10/6/2024
- Postdoctoral fellowship - IFOM
- Recipient
- 1/9/2008
Publications
- The glycocalyx affects the mechanotransductive perception of the topographical microenvironment
- Chighizola Matteo, Dini Tania, Marcotti Stefania, D’Urso Mirko, Piazzoni Claudio, Borghi Francesca, Previdi Anita, Ceriani Laura, Folliero Claudia, Stramer Brian, Lenardi Cristina, Milani Paolo, Podestà Alessandro, Schulte Carsten
- Journal of Nanobiotechnology Vol 20 (2022)
- https://doi.org/10.1186/s12951-022-01585-5
- Mechanotransduction in stem cells
- Ferrai Carmelo, Schulte Carsten
- European Journal of Cell Biology Vol 103 (2024)
- https://doi.org/10.1016/j.ejcb.2024.151417
- Impact of endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) on neutrophil cellular functions
- Saulle Irma, Limanaqi Fiona, Garziano Micaela, Murno Maria Luisa, Artusa Valentina, Strizzi Sergio, Giovarelli Matteo, Schulte Carsten, Aiello Jacopo, Clerici Mario, Vanetti Claudia, Biasin Mara
- Frontiers in Cell and Developmental Biology Vol 12 (2025)
- https://doi.org/10.3389/fcell.2024.1506216
- Native extracellular matrix probes to target patient- and tissue-specific cell-microenvironment interactions by force spectroscopy
- Holuigue H, Nacci L, Di Chiaro P, Chighizola M, Locatelli I, Schulte C, Alfano M, Diaferia G R, Podestà A
- Nanoscale Vol 15, pp. 15382-15395 (2023)
- https://doi.org/10.1039/d3nr01568h
- Nanotopography and microconfinement impact on primary hippocampal astrocyte morphology, cytoskeleton and spontaneous calcium wave signalling
- Previdi Anita, Borghi Francesca, Profumo Filippo, Schulte Carsten, Piazzoni Claudio, Lamanna Jacopo, Racchetti Gabriella, Malgaroli Antonio, Milani Paolo
- Cells Vol 12 (2023)
- https://doi.org/10.3390/cells12020293
- Mechanotransduction
- Schulte Carsten
- Mechanics of Cells and Tissues in Diseases Biomedical Applications: Volume 2 (2023) (2023)
- https://doi.org/10.1515/9783110989380-006
Professional Activities
- Cellular Mechanobiology in Health and Disease: A Tour de Force
- Speaker
- 6/2/2025
- eLife (Journal)
- Peer reviewer
- 2025
- Nanoscale (Journal)
- Peer reviewer
- 2025
- Nature Nanotechnology (Journal)
- Peer reviewer
- 2025
- Reviewer for the BBSRC
- Consultant
- 2025
- A Tour de Force through Cellular Mechanobiology in (Patho)Physiology
- Speaker
- 5/12/2024
Projects
- DTP 2224 University of Strathclyde | Fowler, Dylan
- Schulte, Carsten (Principal Investigator) Reid, Stuart (Co-investigator) Fowler, Dylan (Research Co-investigator)
- 01-Jan-2024 - 01-Jan-2028
- BRAINS Strathclyde CDT 2023 | Hudda, Shruti
- Witte, Kimia (Principal Investigator) Schulte, Carsten (Research Co-investigator) Hudda, Shruti (Research Co-investigator)
- 20-Jan-2024 - 20-Jan-2027
Contact
Dr
Carsten
Schulte
Strathclyde Chancellor's Fellow
Biomedical Engineering
Email: carsten.schulte@strath.ac.uk
Tel: Unlisted