Dr Fraser Scott

Senior Lecturer

Pure and Applied Chemistry

Personal statement

Fraser obtained an MSci(Hons) in Chemistry from the University of Strathclyde in 2009, which was followed by a PhD under the supervision of Prof. Colin J. Suckling, at the same institution awarded in 2012. His doctoral studies spanned computational and synthetic medicinal chemistry, and microbiology, focussed on developing Minor Groove Binders as novel anti-infective agents. During this time, Fraser also obtained a BA(Hons) in Mathematics and Statistics, and a BSc(Hons) in Computing with Mathematical Sciences, with the Open University. Following the completion of his doctorate in 2012, Fraser obtained a PGDE in Chemistry and an MEd in Education studies whilst embarking on a short career in Secondary School education in Scotland. In 2014 he returned to the research group of Prof. Colin J. Suckling at the University of Strathclyde to take up a Post-Doctoral position that included project managing the, now commercial, Minor Grove Binder drug discovery project, alongside medicinal chemistry, chemical biology and microbiology investigations. During this time, Fraser also completed an MSc in Teaching and Learning in Higher Education and was employed as an associate lecturer in Mathematics by the Open University. In 2016, Fraser took up a position as a Senior Lecturer in Organic Chemistry at the University of Lincoln, before moving to a position as Senior Lecturer in Pharmacology at the University of Huddersfield from 2017 to 2019. Fraser is currently a Chancellor's Fellow at the University of Strathclyde

Expertise

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Prize And Awards

RSC Inspirational Committee Award: Recipient; 6/2023
TechConnect Innovation Awardee (Rostra Therapeutics): Recipient; 1/6/2022
ScottishEDGE Winner (Rostra Tx): Recipient; 1/5/2022
ScottishEDGE Finalist (Rostra Tx): Recipient; 29/4/2022
ScottishEDGE Semi-Finalist (Rostra Tx): Recipient; 22/3/2022
Strathclyde Inspire 100 Winner (Rostra Therapeutics): Recipient; 20/11/2021

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Publications

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Publications

MptpB inhibitor improves the action of antibiotics against mycobacterium tuberculosis and nontuberculous mycobacterium avium infections: Rodríguez-Fernández Pablo, Botella Laure, Cavet Jennifer S, Domínguez Jose, Gutierrez Maximiliano G, Suckling Colin J, Scott Fraser J, Tabernero Lydia; ACS Infectious Diseases Vol 10, pp. 170–183 (2024); https://doi.org/10.1021/acsinfecdis.3c00446
ChemDiverse : a chemistry careers activity showcasing diversity: R. Velasquez Sara T, Nimmo Roslyn, Pookayil Teena, Lydon Christopher, Willison Debra, Scott Fraser J; Journal of Chemical Education Vol 100, pp. 3881-3887 (2023); https://doi.org/10.1021/acs.jchemed.3c00355
Can worm-based products reduce inflammatory burden in cerebral small vessel disease?: Lumbreras Perales Cristina, Harnett William, Suckling Colin, Scott Fraser, Van Agtmael Tom, Carswell Hilary; 6th UK Preclinical Stroke Symposium 2023 (2023)
The therapeutic potential of drug-like small molecule analogues of the parasitic worm product ES-62 in cerebral small vessel disease: Lumbreras Perales Cristina, Harnett William, Suckling Colin, Scott Fraser, Van Agtmael Tom, Carswell Hilary; 6th UK Preclinical Stroke Symposium 2023 (2023)
Do parasitic worm products reverse endothelial dysfunction in cerebral small vessel disease?: Lumbreras Perales Cristina, Suckling Colin, Scott Fraser, Harnett William, Van Agtmael Tom, Carswell Hilary; 6th UK Preclinical Stroke Symposium 2023 (2023)
Curate video content to capture students' attention: Scott Fraser; (2023)

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Research

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Research Interests

Fraser's research interests lie within the field of anti-infective drug discovery and STEM education.

Within the context of drug discovery, he is principally focused on developing the novel class of anti-infective agent Strathclyde Minor Groove Binders (S-MGBs) to contribute to global biosecurity threat preparedness. Consequently, his research interests span drug design, chemical synthesis, nucleic acid-ligand interactions and antimicrobial screening, all within the context of bacterial, fungal, parasitic or viral infections.

Fraser has a broad interest in STEM education, heavily informed by his current teaching in HE, and previous experience in Scottish secondary schools as a teaching of chemistry. Current research projects include: the importance of numeracy to STEM education; understanding, and better developing, education of STEM careers in schools and HE; and, enhancing equality, diversity and inclusion in science education.

Fraser welcomes enquiries about post graduate research opportunities in both drug discovery and education research.