Dr Fraser Scott

Senior Lecturer

Pure and Applied Chemistry

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Personal statement

Fraser obtained an MSci(Hons) in Chemistry from the University of Strathclyde in 2009, which was followed by a PhD under the supervision of Prof. Colin J. Suckling, at the same institution awarded in 2012. His doctoral studies spanned computational and synthetic medicinal chemistry, and microbiology, focussed on developing Minor Groove Binders as novel anti-infective agents. During this time, Fraser also obtained a BA(Hons) in Mathematics and Statistics, and a BSc(Hons) in Computing with Mathematical Sciences, with the Open University. Following the completion of his doctorate in 2012, Fraser obtained a PGDE in Chemistry and an MEd in Education studies whilst embarking on a short career in Secondary School education in Scotland. In 2014 he returned to the research group of Prof. Colin J. Suckling at the University of Strathclyde to take up a Post-Doctoral position that included project managing the, now commercial, Minor Grove Binder drug discovery project, alongside medicinal chemistry, chemical biology and microbiology investigations. During this time, Fraser also completed an MSc in Teaching and Learning in Higher Education and was employed as an associate lecturer in Mathematics by the Open University. In 2016, Fraser took up a position as a Senior Lecturer in Organic Chemistry at the University of Lincoln, before moving to a position as Senior Lecturer in Pharmacology at the University of Huddersfield from 2017 to 2019. Fraser is currently a Chancellor's Fellow at the University of Strathclyde

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Publications

Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii
McGee Leah MC, Carpinteyro Sanchez Alemao G, Perieteanu Marina, Eskandari Kaveh, Bian Yan, Mackie Logan, Young Louise, Beveridge Rebecca, Suckling Colin J, Roberts Craig W, Scott Fraser J
Journal of Antimicrobial Chemotherapy (2024)
https://doi.org/10.1093/jac/dkae221
Reduce cognitive load with an augmented reality learning environment : discover how to use augmented reality to help students visualise organic mechanisms
Scott Fraser
(2024)
Spectroscopic, biochemical and computational studies of bioactive DNA minor groove binders targeting 5′-WGWWCW-3′ motif
Alniss Hasan Y, Kemp Bryony M, Holmes Elizabeth, Hoffman Joanna, Ploch Rafal M, Ramadan Wafaa S, Msallam Yousef A, Al-Jubeh Hadeel M, Madkour Moustafa M, Celikkaya Bekir C, Scott Fraser J, El-Awady Raafat, Parkinson John A
Bioorganic Chemistry Vol 148 (2024)
https://doi.org/10.1016/j.bioorg.2024.107414
Examining the impact of the COVID-19 pandemic on student employability skills : an employer’s perspective
Gibson Lorraine, De Pascale Maria Egizia, Burns Emma, Scott Fraser, Walker Sarah
International Journal of Multidisciplinary: Applied Business and Education Research Vol 5, pp. 1207-1221 (2024)
https://doi.org/10.11594/ijmaber.05.04.09
Understanding how students untangle intermolecular forces : Discover how learners use electronegativity to predict the location of dipole−dipole interactions
Scott Fraser
(2024)
Boost maths skills to improve chemistry learning : use these evidence-based tips to help your learners get ahead with chemical calculations
Scott Fraser
(2024)

More publications

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Research Interests

Fraser's research interests lie within the field of anti-infective drug discovery and STEM education.

Within the context of drug discovery, he is principally focused on developing the novel class of anti-infective agent Strathclyde Minor Groove Binders (S-MGBs) to contribute to global biosecurity threat preparedness. Consequently, his research interests span drug design, chemical synthesis, nucleic acid-ligand interactions and antimicrobial screening, all within the context of bacterial, fungal, parasitic or viral infections.

Fraser has a broad interest in STEM education, heavily informed by his current teaching in HE, and previous experience in Scottish secondary schools as a teacher of chemistry. Current research projects include: the importance of numeracy to STEM education; understanding, and better developing, education of STEM careers in schools and HE; and, enhancing equality, diversity and inclusion in science education.

Fraser welcomes enquiries about post graduate research opportunities in both drug discovery and education research.

 

Professional Activities

Routes into PAC Degrees
Recipient
14/6/2024
Towards Gram-negative active S-MGBs
Speaker
12/6/2024
CPD Session: Widening Participation Opportunities in PAC
Recipient
30/5/2024
Pint of Science: Creative Reactions
Recipient
13/5/2024
S-MGBs: From antibacterial to antifungal
Speaker
15/4/2024
MGB-BP-3 as a case study of Strathclyde Minor Groove Binders
Speaker
5/3/2024

More professional activities

Projects

Novel Therapeutics for the Treatment of Candida infections
Scott, Fraser (Principal Investigator) Hunter, Iain (Co-investigator) Suckling, Colin (Co-investigator)
01-Jan-2023 - 28-Jan-2026
New synthesis strategies of a novel class of broad-spectrum anti-infective drug class
Scott, Fraser (Principal Investigator)
Global Research Scholarship, International PhD student, part-self-funded £12,000
01-Jan-2023 - 30-Jan-2026
Design and development of novel agents for the treatment of animal trypanosomiasis
Scott, Fraser (Principal Investigator)
BBSRC DTP-funded
01-Jan-2023 - 30-Jan-2027
Towards the development of a novel class of broad-spectrum anti-infective drugs
Scott, Fraser (Principal Investigator)
~£75,450 Self-funded international PGR student
01-Jan-2023 - 30-Jan-2026
A Scottish perspective on the barriers to progression into, and through, Chemistry HE for those from deprived backgrounds
Willison, Debra (Principal Investigator) Scott, Fraser (Principal Investigator)
04-Jan-2023 - 03-Jan-2024
A Scottish perspective on the barriers to progression into, and through, Chemistry HE for those from deprived backgrounds
Willison, Debra (Principal Investigator) Scott, Fraser (Co-investigator)
01-Jan-2023 - 31-Jan-2024

More projects

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Contact

Dr Fraser Scott
Senior Lecturer
Pure and Applied Chemistry

Email: fraser.j.scott@strath.ac.uk
Tel: 548 2800