Dr Fraser Scott

Strathclyde Chancellor's Fellow

Pure and Applied Chemistry

Fraser obtained an MSci(Hons) in Chemistry from the University of Strathclyde in 2009, which was followed by a PhD under the supervision of Prof. Colin J. Suckling, at the same institution awarded in 2012. His doctoral studies spanned computational and synthetic medicinal chemistry, and microbiology, focussed on developing Minor Groove Binders as novel anti-infective agents. During this time, Fraser also obtained a BA(Hons) in Mathematics and Statistics, and a BSc(Hons) in Computing with Mathematical Sciences, with the Open University. Following the completion of his doctorate in 2012, Fraser obtained a PGDE in Chemistry and an MEd in Education studies whilst embarking on a short career in Secondary School education in Scotland. In 2014 he returned to the research group of Prof. Colin J. Suckling at the University of Strathclyde to take up a Post-Doctoral position that included project managing the, now commercial, Minor Grove Binder drug discovery project, alongside medicinal chemistry, chemical biology and microbiology investigations. During this time, Fraser also completed an MSc in Teaching and Learning in Higher Education and was employed as an associate lecturer in Mathematics by the Open University. In 2016, Fraser took up a position as a Senior Lecturer in Organic Chemistry at the University of Lincoln, before moving to a position as Senior Lecturer in Pharmacology at the University of Huddersfield from 2017 to 2019. Fraser is currently a Chancellor's Fellow at the University of Strathclyde

Publications

Cyrene is a green alternative to DMSO as a solvent for antibacterial drug discovery against ESKAPE pathogens
Camp Jason E, Nyamini Simbarashe B, Scott Fraser J
RSC Medicinal Chemistry (2019)
https://doi.org/10.0.4.15/C9MD00341J
Selective in vitro anti-cancer activity of non-alkylating minor groove binders
Nichol Ryan, Khalaf Abedawn, Sooda Kartheek, Hussain Omar, Griffiths Hollie, Phillips Roger, Javid Farideh, Suckling C J, Allison Simon, Scott Fraser
Medicinal Chemistry Communications Vol 10, pp. 1620-1634 (2019)
https://doi.org/10.1039/C9MD00268E
What do our school reports really say?
Turner Kirsty L, Scott Fraser, Jackson Andrew
Impact: Journal of the Chartered College of Teaching (2019)
Novel minor groove binders cure animal African trypanosomiasis in an in vivo mouse model
Giordani Federica, Khalaf Abedawn I, Gillingwater Kirsten, Munday Jane C, De Koning Harry P, Suckling Colin J, Barrett Michael P, Scott Fraser J
Journal of Medicinal Chemistry Vol 62, pp. 3021-3035 (2019)
https://doi.org/10.1021/acs.jmedchem.8b01847
Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis
Suckling Colin J, Mukherjee Sambuddho, Khalaf Abedawn I, Narayan Ashwini, Scott Fraser J, Khare Sonal, Dhakshinamoorthy Saravanakumar, Harnett Margaret M, Harnett William
Acta Tropica Vol 185, pp. 212-218 (2018)
https://doi.org/10.1016/j.actatropica.2018.05.015
Preparation of a polymeric foam : an activity designed to increase teachers' awareness of the utility of condensation polymerization
Cullen John, Scott Fraser J
Journal of Chemical Education Vol 95, pp. 419-422 (2018)
https://doi.org/10.1021/acs.jchemed.7b00577

more publications

Professional activities

ACS Fall 2020 National Meeting: Division of Small Chemical Businesses
Speaker
16/8/2020
University Of Strathclyde (Organisational unit)
Advisor
1/6/2020
Royal Society of Chemistry (External organisation)
Advisor
1/1/2020
Royal Society of Chemistry (External organisation)
Advisor
1/1/2020
Royal Society of Chemistry (External organisation)
Advisor
1/1/2020
Bioscience Reports (Journal)
Peer reviewer
1/1/2020

more professional activities

Projects

Accelerating the clinical introduction of novel antibiotic combinations effective against Gram-negative pathogens
Scott, Fraser (Principal Investigator)
01-Jan-2020 - 31-Jan-2021
Accelerated introduction of a novel class of resistance-proof COVID-19 drugs: Strathclyde Minor Groove Binders
Scott, Fraser (Principal Investigator)
01-Jan-2020 - 30-Jan-2020
Covid-19 Accelerated introduction of a novel class of resistance-proof antiviral drugs: Strathclyde Minor Groove Binders
Scott, Fraser (Principal Investigator) Suckling, Colin (Co-investigator)
01-Jan-2020 - 30-Jan-2020
Strathclyde COVID-19 Research Portfolio: Novel testing, digital health support and third sector collaboration for impact on social care
Bedford, Tim (Principal Investigator) Corrigan, Damion (Co-investigator) Dunlop, Mark (Co-investigator) Egan, Kieren (Co-investigator) Fleming, Leanne (Co-investigator) Flowers, Paul (Co-investigator) Grealy, Madeleine (Co-investigator) Hoskisson, Paul (Co-investigator) Hunter, Iain (Co-investigator) Janssen, Xanne (Co-investigator) Kirk, Alison (Co-investigator) Knifton, Lee (Co-investigator) Lenhart, Otto (Co-investigator) Maguire, Roma (Co-investigator) Morton, Alec (Co-investigator) Quinn, Neil (Co-investigator) Scott, Fraser (Co-investigator) Suckling, Colin (Co-investigator) Ward, Andrew (Co-investigator) Williams, Lynn (Co-investigator)
01-Jan-2020 - 30-Jan-2020
Tackling Gram-negative infections through a Minor Groove Binder-Siderophore Conjugation Strategy
Scott, Fraser (Principal Investigator)
01-Jan-2020 - 28-Jan-2021
A Socio-economically-informed Approach to Novel Treatments for TB
Scott, Fraser (Principal Investigator) Megiddo, Itamar (Co-investigator)
SFC GCRF Pump Priming Award
01-Jan-2020 - 30-Jan-2020

more projects

Address

Pure and Applied Chemistry
Thomas Graham Building

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