Publications

Multidimensional particle characterisation from in-situ imaging using deep learning and transfer learning: Boyle Christopher, Ferreira Carla, Chen Yi-Chieh, Tachtatzis Christos, Andonovic Ivan, Brown Cameron, Sefcik Jan, Cardona Javier; 21st International Symposium on Industrial Crystallisation (2021)
Effect of glycine on aggregation of citrate-functionalised gold nanoparticles and SERS measurements: Vesga Maria J, McKechnie David, Laing Stacey, Kearns Hayleigh, Faulds Karen, Johnston Karen, Sefcik Jan; Colloids and Surfaces A: Physicochemical and Engineering Aspects Vol 621 (2021); https://doi.org/10.1016/j.colsurfa.2021.126523
Heat transfer and residence time distribution in plug flow continuous oscillatory baffled crystallisers: Briggs Naomi E B, McGinty John, McCabe Callum, Raval Vishal, Sefcik Jan, Florence Alastair J; ACS Omega Vol 6, pp. 18352-18363 (2021); https://doi.org/10.1021/acsomega.1c02215
Extending the SAFT-γ Mie approach to model benzoic acid, diphenylamine, and mefenamic acid : solubility prediction and experimental measurement: Febra Sara A, Bernet Thomas, Mack Corin, McGinty John, Onyemelukwe Iyke I, Urwin Stephanie J, Sefcik Jan, ter Horst Joop H, Adjiman Claire S, Jackson George, Galindo Amparo; Fluid Phase Equilibria Vol 540 (2021); https://doi.org/10.1016/j.fluid.2021.113002
Computer aided design of solvent blends for hybrid cooling and antisolvent crystallization of active pharmaceutical ingredients: Watson Oliver L, Jonuzaj Suela, McGinty John, Sefcik Jan, Galindo Amparo, Jackson George, Adjiman Claire S; Organic Process Research and Development Vol 25, pp. 1123-1142 (2021); https://doi.org/10.1021/acs.oprd.0c00516
Quantification of particle size and concentration using in-line techniques and multivariate analysis: Ferreira Carla, Cardona Javier, Agimelen Okpeafoh, Tachtatzis Christos, Andonovic Ivan, Sefcik Jan, Chen Yi-Chieh; Powder Technology Vol 376, pp. 1-11 (2020); https://doi.org/10.1016/j.powtec.2020.08.015

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.

Professional activities

Multi-sensor Measurements For Quantitative Particle Size And Concentration: Contributor; 20/2/2020
Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.: Contributor; 2020
Multi-sensor in situ measurements of particle size, shape and concentration: Contributor; 2/10/2019
8th World Congress on Particle Technology: Participant; 24/4/2018
Particle Measurement in Process: Contributor; 22/3/2018
Network Plus: Industrial Systems in the Digital Age Conference 2017: Participant; 20/6/2017

More professional activities

Projects

The birth of crystals: new understanding of nucleation by direct measurement: Haw, Mark (Principal Investigator) Lue, Leo (Co-investigator) Sefcik, Jan (Co-investigator); 01-Jan-2020 - 31-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Anker, Samira: Johnston, Karen (Principal Investigator) Sefcik, Jan (Co-investigator) Anker, Samira (Research Co-investigator); 01-Jan-2020 - 01-Jan-2024
Catching nucleation in action using surface enhanced Raman spectroscopy: Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator); 01-Jan-2020 - 30-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James: Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator); 01-Jan-2019 - 01-Jan-2023
RI@S funded summer project: Johnston, Karen (Principal Investigator) Haw, Mark (Co-investigator) Sefcik, Jan (Co-investigator); RI@S funded summer project for Mohammad Talha Dar; 10-Jan-2019 - 05-Jan-2019
GSK PhD studentship top up: Sefcik, Jan (Principal Investigator); 01-Jan-2018 - 30-Jan-2022

More projects

Address

Chemical and Process Engineering
James Weir Building

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Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering