Research Interests
Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.
Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.
We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.
We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.
Professional Activities
Evaluation of methods for particle characterisation from in-line imaging and chord length distribution measurements Contributor17/11/2022Evaluation of methods for particle characterisation from in-line imaging and chord length distribution measurements Contributor19/9/2022Evaluation of Deep Learning methods for particle characterisation from in-line imaging and chord length distribution measurements Contributor18/9/2022Multi-sensor Measurements For Quantitative Particle Size And Concentration Contributor20/2/2020Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance. Contributor2020Multi-sensor in situ measurements of particle size, shape and concentration Contributor2/10/2019
More professional activities
Projects
Effects of mechanical impact and turbulent flow on secondary nucleation Sefcik, Jan (Principal Investigator) 01-Jan-2022 - 30-Jan-2026 Sustainable Pharmaceutical Manufacturing: Computer aided solvent design to minimise solvent use across integrated synthesis, purification & isolation Price, Chris John (Principal Investigator) Kerr, William (Co-investigator) Li, Jun (Co-investigator) Lindsay, David (Co-investigator) Sefcik, Jan (Co-investigator) 11-Jan-2022 - 10-Jan-2025 The birth of crystals: new understanding of nucleation by direct measurement Haw, Mark (Principal Investigator) Lue, Leo (Co-investigator) Sefcik, Jan (Co-investigator) 01-Jan-2020 - 31-Jan-2023 Doctoral Training Partnership 2020-2021 University of Strathclyde | Anker, Samira Johnston, Karen (Principal Investigator) Sefcik, Jan (Co-investigator) Anker, Samira (Research Co-investigator) 01-Jan-2020 - 01-Jan-2024 Catching nucleation in action using surface enhanced Raman spectroscopy Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator) 01-Jan-2020 - 30-Jan-2023 Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator) 01-Jan-2019 - 27-Jan-2023
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