Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering

Publications

Effect of glycine on aggregation of citrate-functionalised gold nanoparticles and SERS measurements
Vesga Maria J, McKechnie David, Laing Stacey, Kearns Hayleigh, Faulds Karen, Johnston Karen, Sefcik Jan
Colloids and Surfaces A: Physicochemical and Engineering Aspects (2021)
Quantification of particle size and concentration using in-line techniques and multivariate analysis
Ferreira Carla, Cardona Javier, Agimelen Okpeafoh, Tachtatzis Christos, Andonovic Ivan, Sefcik Jan, Chen Yi-Chieh
Powder Technology Vol 376, pp. 1-11 (2020)
https://doi.org/10.1016/j.powtec.2020.08.015
Clustering behaviour of polyaromatic compounds mimicking natural asphaltenes
Simionesie Dorin, O’Callaghan Greg, Costa Joao LLFS, Giusti Leonardo, Kerr William J, Sefcik Jan, Mulheran Paul A, Zhang Zhenyu J
Colloids and Surfaces A: Physicochemical and Engineering Aspects Vol 603 (2020)
https://doi.org/10.1016/j.colsurfa.2020.125221
Computer-aided solvent mixture design for the crystallization and isolation of mefenamic acid
Jonuzaj Suela, Watson Oliver L, Ottoboni Sara, Price Chris J, Sefcik Jan, Galindo Amparo, Jackson George, Adjiman Claire S
30th European Symposium on Computer Aided Process Engineering Computer Aided Chemical Engineering Vol 48, pp. 649-654 (2020)
https://doi.org/10.1016/B978-0-12-823377-1.50109-9
Effect of process conditions on particle size and shape in continuous antisolvent crystallisation of lovastatin
McGinty John, Chong Magdalene W S, Manson Andrew, Brown Cameron J, Nordon Alison, Sefcik Jan
Crystals Vol 10 (2020)
https://doi.org/10.3390/cryst10100925
Influence of ions and pH on formation of solid and liquid-like melanin
Chen Yi-chieh, Kendall Thomas, Yip Philip, Davy Alastair, Sefcik Jan, Sutter Jens U
ACS Omega Vol 5, pp. 25059-25068 (2020)
https://doi.org/10.1021/acsomega.0c01953

More publications

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.   

Professional activities

Multi-sensor Measurements For Quantitative Particle Size And Concentration
Contributor
20/2/2020
Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.
Contributor
2020
Multi-sensor in situ measurements of particle size, shape and concentration
Contributor
2/10/2019
8th World Congress on Particle Technology
Participant
24/4/2018
Particle Measurement in Process
Contributor
22/3/2018
15th Scandinavian Symposium on Chemometrics
Participant
20/6/2017

More professional activities

Projects

The birth of crystals: new understanding of nucleation by direct measurement
Haw, Mark (Principal Investigator) Lue, Leo (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 31-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Anker, Samira
Johnston, Karen (Principal Investigator) Sefcik, Jan (Co-investigator) Anker, Samira (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Catching nucleation in action using surface enhanced Raman spectroscopy
Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 30-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James
Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
RI@S funded summer project
Johnston, Karen (Principal Investigator) Haw, Mark (Co-investigator) Sefcik, Jan (Co-investigator)
RI@S funded summer project for Mohammad Talha Dar
10-Jan-2019 - 05-Jan-2019
Doctoral Training Partnership 2018-19 University of Strathclyde | Merrilees, Martyn
Lau, K. H. Aaron (Principal Investigator) Sefcik, Jan (Co-investigator) Merrilees, Martyn (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022

More projects

Address

Chemical and Process Engineering
James Weir Building

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