Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering


Co-crystal phase diagram determination by the solution addition method
Svoboda Vaclav, Venkatramanan Raghunath, Jaap Mairi, Lue Leo, ter Horst Joop H, Sefcik Jan
Crystal Growth and Design Vol 22, pp. 3376-3384 (2022)
Modelling diffusive mixing in antisolvent crystallization
Miller Russell, Sefcik Jan, Lue Leo
Crystal Growth and Design Vol 22, pp. 2192-2207 (2022)
Temperature dependence of solubility predicted from thermodynamic data measured at a single temperature : application to α, β and γ-glycine
Manson Andrew, Sefcik Jan, Lue Leo
Crystal Growth and Design Vol 22, pp. 1691-1706 (2022)
Effect of oscillatory flow conditions on crystalliser fouling investigated through non-invasive imaging
Sheridan Rachel, Cardona Javier, Tachtatzis Christos, Chen Yi-Chieh, Cleary Alison, Briggs Naomi E B, Florence Alastair, Atkinson Robert, Michie Craig, Andonovic Ivan, Sefcik Jan
Chemical Engineering Science (2021)
Multidimensional particle characterisation from in-situ imaging using deep learning and transfer learning
Boyle Christopher, Ferreira Carla, Chen Yi-Chieh, Tachtatzis Christos, Andonovic Ivan, Brown Cameron, Sefcik Jan, Cardona Javier
21st International Symposium on Industrial Crystallisation (2021)
Heat transfer and residence time distribution in plug flow continuous oscillatory baffled crystallisers
Briggs Naomi E B, McGinty John, McCabe Callum, Raval Vishal, Sefcik Jan, Florence Alastair J
ACS Omega Vol 6, pp. 18352-18363 (2021)

More publications

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.   

Professional activities

Multi-sensor Measurements For Quantitative Particle Size And Concentration
Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.
Multi-sensor in situ measurements of particle size, shape and concentration
8th World Congress on Particle Technology
Particle Measurement in Process
Network Plus: Industrial Systems in the Digital Age Conference 2017

More professional activities


The birth of crystals: new understanding of nucleation by direct measurement
Haw, Mark (Principal Investigator) Lue, Leo (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 31-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Anker, Samira
Johnston, Karen (Principal Investigator) Sefcik, Jan (Co-investigator) Anker, Samira (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Catching nucleation in action using surface enhanced Raman spectroscopy
Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 30-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James
Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
RI@S funded summer project
Johnston, Karen (Principal Investigator) Haw, Mark (Co-investigator) Sefcik, Jan (Co-investigator)
RI@S funded summer project for Mohammad Talha Dar
10-Jan-2019 - 05-Jan-2019
Doctoral Training Partnership 2018-19 University of Strathclyde | Miller, Russell
Sefcik, Jan (Principal Investigator) Lue, Leo (Co-investigator) Miller, Russell (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022

More projects


Chemical and Process Engineering
James Weir Building

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