Publications

Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly: Hasan Abshar, Saxena Varun, Castelletto Valeria, Zimbitas Georgina, Seitsonen Jani, Ruokolainen Janne, Pandey Lalit M, Sefcik Jan, Hamley Ian W, Lau King Hang Aaron; Frontiers in Chemistry Vol 8 (2020); https://doi.org/10.3389/fchem.2020.00416
Interfacial concentration effect facilitates heterogeneous nucleation from solution: McKechnie David, Anker Samira, Zahid Saraf, Mulheran Paul A, Sefcik Jan, Johnston Karen; Journal of Physical Chemistry Letters Vol 11, pp. 2263-2271 (2020); https://doi.org/10.1021/acs.jpclett.0c00540
Nucleation control in continuous crystallization: Sefcik Jan, Ter Horst Joop, McGinty John, Price Chris John; The Handbook of Continuous Crystallization (2020) (2020)
Investigation of molecular and mesoscale clusters in undersaturated glycine aqueous solutions: Zimbitas Georgina, Jawor-Baczynska Anna, Vesga Maria Jazmin, Javid Nadeem, Moore Barry D, Parkinson John, Sefcik Jan; Colloids and Surfaces A: Physicochemical and Engineering Aspects Vol 579 (2019); https://doi.org/10.1016/j.colsurfa.2019.123633
"Curdling" of soymilk in coffee : a study of the phase behaviour of soymilk coffee mixtures: Brown Mairi, Laitano Francesca, Williams Calum, Gibson Bruce, Haw Mark, Sefcik Jan, Johnston Karen; Food Hydrocolloids Vol 95, pp. 462-467 (2019); https://doi.org/10.1016/j.foodhyd.2019.04.032
Resolution control in a continuous preferential crystallization process: Dunn Andrew S, Svoboda Vaclav, Sefcik Jan, ter Horst Joop H; Organic Process Research and Development Vol 23, pp. 2031-2041 (2019); https://doi.org/10.1021/acs.oprd.9b00275

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.

Professional activities

8th World Congress on Particle Technology: Participant; 24/4/2018
15th Scandinavian Symposium on Chemometrics: Participant; 20/6/2017
Network Plus: Industrial Systems in the Digital Age Conference 2017: Participant; 20/6/2017
18th International Conference on Near Infrared Spectroscopy: Participant; 13/6/2017
EuroPACT 2017: Participant; 10/5/2017
European Summer School on Crystal Nucleation: Invited speaker; 20/6/2016

more professional activities

Projects

Catching nucleation in action using surface enhanced Raman spectroscopy: Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator); 01-Jan-2020 - 31-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James: Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator); 01-Jan-2019 - 01-Jan-2022
RI@S funded summer project: Johnston, Karen (Principal Investigator) Haw, Mark (Co-investigator) Sefcik, Jan (Co-investigator); RI@S funded summer project for Mohammad Talha Dar; 10-Jan-2019 - 05-Jan-2019
Doctoral Training Partnership 2018-19 University of Strathclyde | Merrilees, Martyn: Lau, K. H. Aaron (Principal Investigator) Sefcik, Jan (Co-investigator) Merrilees, Martyn (Research Co-investigator); 01-Jan-2018 - 01-Jan-2022
GSK PhD studentship top up: Sefcik, Jan (Principal Investigator); 01-Jan-2018 - 30-Jan-2022
Doctoral Training Partnership 2018-19 University of Strathclyde | Cashmore, Andrew: Sefcik, Jan (Principal Investigator) Haw, Mark (Co-investigator) Cashmore, Andrew (Research Co-investigator); 01-Jan-2018 - 01-Jan-2022

more projects

Address

Chemical and Process Engineering
James Weir Building

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Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering