Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering

Publications

Conundrum of γ glycine nucleation revisited : to stir or not to stir?
Vesga Maria J, McKechnie David, Mulheran Paul A, Johnston Karen, Sefcik Jan
CrystEngComm, pp. 1-15 (2019)
https://doi.org/10.1039/c8ce01829d
The impact of deuterium oxide on the properties of resorcinol-formaldehyde gels
Prostredny Martin, Ballantine Jack, Sefcik Jan, Fletcher Ashleigh J
Journal of Sol-Gel Science and Technology Vol 89, pp. 21–28 (2019)
https://doi.org/10.1007/s10971-018-4595-0
Engineering of acetaminophen particle attributes using a wet milling crystallisation platform
Ahmed Bilal, Brown Cameron J, McGlone Thomas, Bowering Deborah L, Sefcik Jan, Florence Alastair J
International Journal of Pharmaceutics Vol 554, pp. 201-211 (2019)
https://doi.org/10.1016/j.ijpharm.2018.10.073
Measuring secondary nucleation through single crystal seeding
Briuglia Maria L, Sefcik Jan, Horst Joop H ter
Crystal Growth and Design Vol 19, pp. 421-429 (2019)
https://doi.org/10.1021/acs.cgd.8b01515
Multi-sensor inline measurements of crystal size and shape distributions during high shear wet milling of crystal slurries
Agimelen Okpeafoh S, Svoboda Vaclav, Ahmed Bilal, Cardona Javier, Dziewierz Jerzy, Brown Cameron J, McGlone Thomas, Cleary Alison, Tachtatzis Christos, Michie Craig, Florence Alastair J, Andonovic Ivan, Mulholland Anthony J, Sefcik Jan
Advanced Powder Technology Vol 29, pp. 2987-2995 (2018)
https://doi.org/10.1016/j.apt.2018.09.003
Image analysis framework with focus evaluation for in situ characterisation of particle size and shape attributes
Cardona Javier, Ferreira Carla, McGinty John, Hamilton Andrew, Agimelen Okpeafoh S, Cleary Alison, Atkinson Robert, Michie Craig, Marshall Stephen, Chen Yi-Chieh, Sefcik Jan, Andonovic Ivan, Tachtatzis Christos
Chemical Engineering Science Vol 191, pp. 208-231 (2018)
https://doi.org/10.1016/j.ces.2018.06.067

more publications

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.   

Professional activities

Multi-sensor Measurements For Quantitative Particle Size And Concentration Information in Crystal Slurries
Contributor
24/4/2018
MULTI-SENSOR MEASUREMENTS OF QUANTITATIVE PARTICLE SIZE AND SHAPE INFORMATION
Contributor
20/6/2017
Extracting and monitoring particle size distribution information for pharmaceutical crystallisation process using spatially and angularly resolved Visible-NIR Spectra
Contributor
13/6/2017
Modelling of particle size and shape distribution in pharmaceutical suspensions and the effects on UV-vis-NIR
Contributor
10/5/2017
European Summer School on Crystal Nucleation
Invited speaker
20/6/2016
Crystallize COST Action CM1402 Annual Meeting
Keynote/plenary speaker
6/4/2016

more professional activities

Projects

GSK PhD studentship top up
Sefcik, Jan (Principal Investigator)
01-Jan-2018 - 30-Jan-2022
DTP 2018-19 University of Strathclyde | Merrilees, Martyn
Lau, K. H. Aaron (Principal Investigator) Sefcik, Jan (Co-investigator) Merrilees, Martyn (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022
DTP 2018-19 University of Strathclyde | Miller, Russell
Sefcik, Jan (Principal Investigator) Lue, Leo (Co-investigator) Miller, Russell (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022
DTP 2018-19 University of Strathclyde | Cashmore, Andrew
Sefcik, Jan (Principal Investigator) Haw, Mark (Co-investigator) Cashmore, Andrew (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022
Placement Agreement
Sefcik, Jan (Principal Investigator)
08-Jan-2018 - 10-Jan-2018
CMAC Core project: Antisolvent
Florence, Alastair (Principal Investigator) Sefcik, Jan (Co-investigator)
01-Jan-2017 - 30-Jan-2019

more projects

Address

Chemical and Process Engineering
James Weir Building

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