Professor Jan Sefcik

Head Of Department

Chemical and Process Engineering


Tuning interfacial concentration enhancement through dispersion interactions to facilitate heterogeneous nucleation
McKechnie David, Mulheran Paul A, Sefcik Jan, Johnston Karen
Journal of Physical Chemistry C (2022)
Continuous crystallisation of organic salt polymorphs
McGinty John, Svoboda Vaclav, Macfhionnghaile Pol, Wheatcroft Helen, Price Chris J, Sefcik Jan
Frontiers in Chemical Engineering Vol 4 (2022)
Phase diagram determination and process development for continuous antisolvent crystallizations
Mack Corin, Hoffmann Johannes, Sefcik Jan, ter Horst Joop H
Crystals Vol 12 (2022)
Molecular dynamics investigation of clustering in aqueous glycine solutions
Sweatman Martin B, Afify Nasser D, Ferreiro-Rangel Carlos A, Jorge Miguel, Sefcik Jan
Journal of Physical Chemistry B Vol 126, pp. 4711-4722 (2022)
Crystal nucleation rates from induction time measurements and microfluidic devices
Powell Daniel M, Sefcik Jan, Zagnoni Michele, ter Horst Joop H
CMAC Annual Open Day 2022, pp. 60-60 (2022)
A structured approach to implementation of measurements : crystallisation in the mefenamic acid MicroFactory
Chong Magdalene, Li Wei, Brown Cameron, McGinty John, Robertson Murray, Johnston Blair, Sefcik Jan, Benyahia Brahim, Rielly Chris, Nordon Alison
CMAC Annual Open Day 2022, pp. 61-61 (2022)

More publications

Research interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.   

Professional activities

Evaluation of Deep Learning methods for particle characterisation from in-line imaging and chord length distribution measurements
Multi-sensor Measurements For Quantitative Particle Size And Concentration
Integrated Filtration and Washing Modelling to Predict Continuous Isolation Performance.
Multi-sensor in situ measurements of particle size, shape and concentration
8th World Congress on Particle Technology
Particle Measurement in Process

More professional activities


The birth of crystals: new understanding of nucleation by direct measurement
Haw, Mark (Principal Investigator) Lue, Leo (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 31-Jan-2023
Doctoral Training Partnership 2020-2021 University of Strathclyde | Anker, Samira
Johnston, Karen (Principal Investigator) Sefcik, Jan (Co-investigator) Anker, Samira (Research Co-investigator)
01-Jan-2020 - 01-Jan-2024
Catching nucleation in action using surface enhanced Raman spectroscopy
Johnston, Karen (Principal Investigator) Faulds, Karen (Co-investigator) Sefcik, Jan (Co-investigator)
01-Jan-2020 - 30-Jan-2023
Doctoral Training Partnership 2018-19 University of Strathclyde | Flannigan, James
Haw, Mark (Principal Investigator) Sefcik, Jan (Co-investigator) Flannigan, James (Research Co-investigator)
01-Jan-2019 - 01-Jan-2023
RI@S funded summer project
Johnston, Karen (Principal Investigator) Haw, Mark (Co-investigator) Sefcik, Jan (Co-investigator)
RI@S funded summer project for Mohammad Talha Dar
10-Jan-2019 - 05-Jan-2019
Doctoral Training Partnership 2018-19 University of Strathclyde | Cashmore, Andrew
Sefcik, Jan (Principal Investigator) Haw, Mark (Co-investigator) Cashmore, Andrew (Research Co-investigator)
01-Jan-2018 - 01-Jan-2022

More projects


Chemical and Process Engineering
James Weir Building

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