Dr Martin Ward
Research Fellow
Continuous Manufacturing And Crystallisation
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Publications
- Exploring the effects of high pressure on hydrogen bonding in pharmaceutical cocrystals : a systematic study of pyridine dicarboxylic acid systems using synchrotron and neutron diffraction
- Ward Martin R, Bull Craig L, Funnell Nicolas P, Warren Mark R, Oswald Iain DH
- International Journal of Pharmaceutics Vol 647 (2023)
- https://doi.org/10.1016/j.ijpharm.2023.123514
- Pushing technique boundaries to probe conformational polymorphism
- Ward Martin R, Taylor Christopher R, Mulvee Matthew T, Lampronti Giulio I, Belenguer Ana M, Steed Jonathan W, Day Graeme M, Oswald Iain D H
- Crystal Growth and Design Vol 23, pp. 7217-7230 (2023)
- https://doi.org/10.1021/acs.cgd.3c00641
- Pressure-induced postsynthetic cluster anion substitution in a MIL-53 topology scandium metal–organic framework
- Thom Alexander J R, Turner Gemma F, Davis Zachary H, Ward Martin R, PakamorÄ— Ignas, Hobday Claire L, Allan David R, Warren Mark R, Leung Wai L W, Oswald Iain D H, Morris Russell E, Moggach Stephen A, Ashbrook Sharon E, Forgan Ross S
- Chemical Science Vol 14, pp. 7716-7724 (2023)
- https://doi.org/10.1039/D3SC00904A
- Exploring the thermal behaviour of the solvated structures of Nifedipine
- Jones Eleanor C L, Goldsmith Kate E, Ward Martin R, Bimbo Luis M, Oswald Iain D H
- Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials Vol 79, pp. 164-175 (2023)
- https://doi.org/10.1107/s2052520623001282
- Crystal structure of a copper-mefenamate complex solvated with diglyme and water
- Chong Magdalene W S, Ottoboni Sara, Martin Alan R G, Bowering Deborah, Price Chris J, Nordon Alison, Oswald Iain D H, Ward Martin R
- Acta Crystallographica Section E: Structure Reports Vol 78 (2022)
- https://doi.org/10.1107/S2056989022010647
- Recovery of high-pressure solid forms to ambient conditions
- Ward Martin, Oswald Iain D H
- CMAC Annual Open Day 2022, pp. 43-43 (2022)
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Professional Activities
- Application of calibration free approaches for rapid polymorph discrimination by low frequency Raman spectroscopy
- Contributor
- 25/4/2024
- Recovery of high pressure solid forms to ambient pressure
- Speaker
- 9/7/2019
Projects
- Investigation of pyrazine:diacid co-crystal systems at high pressure
- Oswald, Iain (Principal Investigator) Ward, Martin (Co-investigator) Bull, Craig L. (Co-investigator) Funnell, Nicholas P. (Co-investigator)
- The aim of this proposal is to follow the changes in the hydrogen bonding
interaction in the pyrazine:oxalic acid and the Pyrazine:maleic acid co-crystals to complete our combined synchrotron and neutron study of the pyrazine:diacid
system. - 01-Jan-2020 - 06-Jan-2020
- Investigation of maleic-d2 acid isomerization at high pressure
- Ward, Martin (Principal Investigator) Oswald, Iain (Co-investigator)
- We will use central facilities time (ISIS neutron and muon facility) to study the conversion of maleic to fumaric acid under high pressure and temperature conditions. Experiments performed in-house show that temperature of pressure alone do not significantly influence the conversion of maleic to fumaric acid; however, the combination of both does result in successful conversion. Neutron experiments will elucidate the conversion in-situ, as it progresses, and allow us to identify ciritcal conditions of temperature and pressure to cause this conversion.
- 26-Jan-2019
- laser-induced nucleation at extreme conditions
- Ward, Martin (Principal Investigator) Oswald, Iain (Co-investigator) Alexander, Andrew J (Co-investigator)
- In this work we will explore the use of a focussed beam of light to cause crystals to form inside our high-pressure sample holder. The use of laser light (pulse and continuous) has been shown to be able to cause nucleation (the first step of crystallization) to occur at ambient conditions, we will continue with this to (i) see if it is applicable to high pressure conditions, and (ii) develop the methodology to assist with nucleation studies at extreme conditions.
- 16-Jan-2019
- small-angle X-ray scattering at high pressure
- Ward, Martin (Principal Investigator)
- Experiments performed in order to assess the possibility to collect good solution phase SAXS data using a conventional diamond anvil cell high pressure cell.
- 11-Jan-2018 - 13-Jan-2018
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Contact
Dr
Martin
Ward
Research Fellow
Continuous Manufacturing And Crystallisation
Email: martin.ward@strath.ac.uk
Tel: Unlisted