Dr Michele Zagnoni

Reader

Electronic and Electrical Engineering

Personal statement

Michele Zagnoni's research is based on the development of new microsystems for basic biology investigation, diagnosis and treatment of disease using microfluidic and lab-on-a-chip technologies. More information on: www.zagnonilab.com

Expertise

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Area of Expertise

Microfabrication of polymeric structures

Theoretical and experimental expertise in fluid dynamics at the microscale

On chip cell culture

Organ on a chip

Bioimaging

Miniaturised bioassay

Prize And Awards

Member of Departmental Safety Committee: Recipient; 5/2011

More prizes and awards

Qualifications

08/2013 Member of the EPSRC Peer Review College

06/2013 Affiliate Membership to the Royal Society of Chemistry

10/2012: SCQF Certificate for Biosafety Practitioner Level 1

10/2012: PostGraduate Certificate in Advanced Academic Studies

04/2006: Ph.D. degree in Electronic Engineering and Computer Science

11/2002: Italian state certification for the practice of engineering as a profession (Chartered Engineer)

10/2002: Dr. Eng. degree (5 year degree) in Electronic Engineering (Bioengineering qualification)

Publications

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Publications

A high-fidelity microfluidic platform reveals retrograde propagation as the main mechanism of α-Synuclein spread in human neurons: Vroman Rozan, de Lichtervelde Lorenzo, Singh Dolt Karamjit, Robertson Graham, Kriek Marco, Barbato Michela, Cholewa-Waclaw Justyna, Kunath Tilo, Downey Patrick, Zagnoni Michele; npj Parkinson's Disease (2025); https://doi.org/10.1038/s41531-025-00936-x
Functional, patient-derived 3D tri-culture models of the uterine wall in a microfluidic array: Busch Caroline, Hill Christopher J, Paterson Karla, Mellin Ronan, Zagnoni Michele, Hapangama Dharani K, Sandison Mairi E; Human Reproduction Vol 39, pp. 2537–2550 (2024); https://doi.org/10.1093/humrep/deae214
Hormone-responsive, patient-derived models of the uterine wall in a microfluidic array: Busch Caroline, Hill Christopher J, Paterson Karla, Zagnoni Michele, Hapangama Dharani, Sandison Mairi E; Tissue and Cell Engineering Society Conference 2024 (2024)
Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach: Busch Caroline, Mulholland Theresa, Zagnoni Michele, Dalby Matthew, Berry Catherine, Wheadon Helen; Cell Communication and Signalling Vol 21 (2023); https://doi.org/10.1186/s12964-023-01363-2
Targeted CAR-T killing in 3D microfluidic cancer-stromal co-cultures: Zagnoni Michele, Paterson Karla; BioMedEng23 (2023)
Development of an in vitro model of spatiotemporal oxygen-glucose deprivation for the study of microglial migration after stroke: Aruvornlop Panicha, Zagnoni Michele, Carswell Hilary; 6th UK Preclinical Stroke Symposium 2023 (2023)

More publications

Teaching

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Teaching

Teaching Staff for the course EE312 - Instrumentation and Microcontrollers (3^rd year) at the University of Strathclyde.

Support Staff for the course EE105 - Electronic Techniques and Design (1^st year) at the University of Strathclyde.

Teaching Staff for Small Group Tutorials (SGT) at the University of Strathclyde.

Research

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Research Interests

We use microfluidics for the development of screening and diagnostic systems for healthcare applications, including fundamental biological research, drug screening and personalized medicine therapy, for the creation of organ-on-a-chip in vitro models and for synthetic biology applications.