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Dr Michele Zagnoni

Senior Lecturer

Electronic and Electrical Engineering

Personal statement

Michele Zagnoni's research is based on the development of new microsystems for basic biology investigation, diagnosis and treatment of disease using microfluidic and lab-on-a-chip technologies. More information on: www.zagnonilab.com

Expertise

Has expertise in:

    Microfabrication of polymeric structures

    Theoretical and experimental expertise in fluid dynamics at the microscale

    On chip cell culture

    Organ on a chip

    Bioimaging

    Miniaturised bioassay

Prizes and awards

Member of Departmental Safety Committee
Recipient
5/2011

more prizes and awards

Publications

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons
Ritchie Louise, Tate Rothwelle, Chamberlain Luke H., Robertson Graham, Zagnoni Michele, Sposito Teresa, Wray Selina, Wright John A., Bryant Clare E., Gay Nicholas J., Bushell Trevor J.
Neuropharmacology Vol 135, pp. 1-10, (2018)
http://dx.doi.org/10.1016/j.neuropharm.2018.02.025
A microfluidic platform for the characterisation of CNS active compounds
MacKerron Christopher, Robertson Graham, Zagnoni Michele, Bushell Trevor
Scientific Reports, (2017)
http://dx.doi.org/10.1038/s41598-017-15950-0
Perfusion based microfluidic system for pharmacological profiling of neuronal networks
MacKerron C., Robertson G., Bushell T.J., Zagnoni M.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), pp. 445-446, (2016)
Dementia on a chip : monitoring synaptic dysfunction of patient derived human neurons
Robertson G., Sposito T., Wray S., Hardy J., Bushell T.J., Zagnoni M.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), pp. 379-380, (2016)
On-chip formation of 3D spheroids for patient-derived tissue screening
Christ T., Payne S., Yan Y., Ren J., Edwards J., Boyd M., Zagnoni M.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), pp. 577-578, (2016)
From emulsion to single-phase microfluidics : an integrated approach to culture and perfusion of multicellular spheroids
McMillan Kay S, Boyd Marie, Zagnoni Michele
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), pp. 399-400, (2016)

more publications

Teaching

Teaching Staff for the course EE312 - Instrumentation and Microcontrollers (3rd year) at the University of Strathclyde.

Support Staff for the course EE105 - Electronic Techniques and Design (1st year) at the University of Strathclyde.

Teaching Staff for Small Group Tutorials (SGT) at the University of Strathclyde.

Research interests

We use microfluidics for the development of screening and diagnostic systems for healthcare applications, including fundamental biological research, drug screening and personalized medicine therapy, for the creation of organ-on-a-chip in vitro models and for synthetic biology applications.

Professional activities

In vitro microfluidic systems for studying cell functionality and compound/particle screening
Contributor
10/2014
Microfluidic technologies for screening neuronal network functionality
Contributor
24/9/2014
Microfluidics for cell culture and bioassay development
Contributor
4/2014
Global Engagement Bionanotechnology workshop
Participant
12/3/2013
Reviewer of proposals submitted to the European Research Council (ERC)
External Examiner
2/2012
Reviewer of responsive mode grant proposals for EPSRC
External Examiner
1/11/2011

more professional activities

Projects

Industrial Case Account 2016 | Robertson, Jack
Burley, Glenn (Principal Investigator) Zagnoni, Michele (Co-investigator) Robertson, Jack (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
An EPSRC Life Sciences Interface Doctoral Training Centre for Medical Devices | Robertson, Graham
Bushell, Trevor (Principal Investigator) Zagnoni, Michele (Co-investigator) Robertson, Graham (Research Co-investigator)
Period 01-Oct-2010 - 04-Sep-2015
An EPSRC Life Sciences Interface Doctoral Training Centre for Medical Devices | Wilson, Calum
McCarron, John (Principal Investigator) Zagnoni, Michele (Co-investigator) Wilson, Calum (Research Co-investigator)
Period 01-Oct-2010 - 22-Apr-2015
How are repairing brain cells successfully recruited to multiple sclerosis lesions?
Zagnoni, Michele (Principal Investigator)
Period 01-Mar-2017 - 29-Feb-2020
Microfluidic systems to measure the pathological spread of alpha-synuclein in iPSC neurons
Zagnoni, Michele (Principal Investigator)
Period 01-Mar-2016 - 31-Mar-2019
Medical Devices Doctoral Training Centre Renewal | Wilson, Calum
McCarron, John (Principal Investigator) Zagnoni, Michele (Co-investigator) Wilson, Calum (Research Co-investigator)
Period 01-Oct-2010 - 22-Apr-2015

more projects

Address

Electronic and Electrical Engineering
Royal College Building

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