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Dr Michele Zagnoni

Senior Lecturer

Electronic and Electrical Engineering

Personal statement

Michele Zagnoni's research is based on the development of new microsystems for basic biology investigation, diagnosis and treatment of disease using microfluidic and lab-on-a-chip technologies. More information on: www.zagnonilab.com

Expertise

Has expertise in:

    Microfabrication of polymeric structures

    Theoretical and experimental expertise in fluid dynamics at the microscale

    On chip cell culture

    Organ on a chip

    Bioimaging

    Miniaturised bioassay

Prizes and awards

Member of Departmental Safety Committee
Recipient
5/2011

more prizes and awards

Publications

Surface enhanced Raman scattering (SERS) based microfluidics for single cell analysis
Willner Marjorie R., McMillan Kay, Graham Duncan, Vikesland Peter J., Zagnoni Michele
Analytical Chemistry, (2018)
Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient
Mulholland Theresa, McAllister Milly, Patek Samantha, Flint David, Underwood Mark, Sim Alexander, Edwards Joanne, Zagnoni Michele
Scientific Reports, (2018)
Drug screening of biopsy-derived multicellular spheroids using microfluidic technology
Mulholland Theresa E., McAllister Milly, Patek Samantha, Flint David, Underwood Mark, Sim Alexander, Edwards Joanne, Zagnoni Michele
Cancer Research Vol 78, (2018)
http://dx.doi.org/10.1158/1538-7445.AM2018-5024
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons
Ritchie Louise, Tate Rothwelle, Chamberlain Luke H., Robertson Graham, Zagnoni Michele, Sposito Teresa, Wray Selina, Wright John A., Bryant Clare E., Gay Nicholas J., Bushell Trevor J.
Neuropharmacology Vol 135, pp. 1-10, (2018)
http://dx.doi.org/10.1016/j.neuropharm.2018.02.025
A microfluidic platform for the characterisation of CNS active compounds
MacKerron Christopher, Robertson Graham, Zagnoni Michele, Bushell Trevor
Scientific Reports, (2017)
http://dx.doi.org/10.1038/s41598-017-15950-0
Investigating mechanisms of protein transport and assembly at the node of Ranvier
Grunewald E., Malavasi E., Ghosh A., Zagnoni M., Sherman D., Brophy P.
Glia Vol 65, (2017)
http://dx.doi.org/10.1002/glia.23157

more publications

Teaching

Teaching Staff for the course EE312 - Instrumentation and Microcontrollers (3rd year) at the University of Strathclyde.

Support Staff for the course EE105 - Electronic Techniques and Design (1st year) at the University of Strathclyde.

Teaching Staff for Small Group Tutorials (SGT) at the University of Strathclyde.

Research interests

We use microfluidics for the development of screening and diagnostic systems for healthcare applications, including fundamental biological research, drug screening and personalized medicine therapy, for the creation of organ-on-a-chip in vitro models and for synthetic biology applications.

Professional activities

OncoScreen: a microfluidic platform for animal-free 3D oncology
Speaker
26/10/2018
Cell Model System Summer School
Participant
7/6/2018
Chiara Da San Martino
Host
5/2018
PhD External Examiner
Examiner
4/2018
Giuseppe Lamanna
Host
1/2018
PhD External Examiner
Examiner
10/2017

more professional activities

Projects

A microfluidic approach to investigating vascular cell fate at the single-cell level
Zagnoni, Michele (Principal Investigator) Sandison, Mairi (Co-investigator)
Period 01-Oct-2018 - 30-Sep-2022
Industrial Case Account 2016 | Robertson, Jack
Burley, Glenn (Principal Investigator) Zagnoni, Michele (Co-investigator) Robertson, Jack (Research Co-investigator)
Period 01-Oct-2016 - 01-Oct-2020
An EPSRC Life Sciences Interface Doctoral Training Centre for Medical Devices | Robertson, Graham
Bushell, Trevor (Principal Investigator) Zagnoni, Michele (Co-investigator) Robertson, Graham (Research Co-investigator)
Period 01-Oct-2010 - 04-Sep-2015
An EPSRC Life Sciences Interface Doctoral Training Centre for Medical Devices | Wilson, Calum
McCarron, John (Principal Investigator) Zagnoni, Michele (Co-investigator) Wilson, Calum (Research Co-investigator)
Period 01-Oct-2010 - 22-Apr-2015
How are repairing brain cells successfully recruited to multiple sclerosis lesions?
Zagnoni, Michele (Principal Investigator)
Period 01-Mar-2017 - 29-Feb-2020
Microfluidic systems to measure the pathological spread of alpha-synuclein in iPSC neurons
Zagnoni, Michele (Principal Investigator)
Period 01-Mar-2016 - 31-Mar-2019

more projects

Address

Electronic and Electrical Engineering
Royal College Building

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