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Chemical processing, tubes

MScAdvanced Pharmaceutical Manufacturing

Why this course?

This unique Masters course trains you in key aspects of modern manufacturing approaches suitable for pharmaceuticals and high-value chemicals.

It's designed to produce highly-skilled graduates in continuous manufacturing science and technology to meet the growing demands for expertise in this area. You’ll be trained to take up jobs in the food, chemical and pharmaceutical industries.

The course is aligned with the EPSRC Doctoral Training Centre in Continuous Manufacturing & Crystallisation (CMAC). It’s supported by academic staff from across the University, six academic partners and CMAC's strategic partners (AstraZeneca, GlaxoSmithKline, Novartis).

You’ll study

The course consists of taught classes along with practical classes from October to April.

If you successfully complete all assessments you’ll then undertake a 10-week research project. This can be at the University or with an external company or organisation. You’ll submit a thesis at the end of August.

You'll learn about:

  • pharmaceutical development and production
  • continuous manufacturing processes
  • crystallisation mechanisms
  • manufacturing processes as they related to the modern pharmaceutical industry
  • transferable, professional skills
  • Process Analytical Technology (PAT) and data analytic
  • quality assurance
  • Management and Quality-by-Design systems.

Facilities

Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS)

The Strathclyde Institute of Pharmacy & Biomedical Sciences offers an excellent environment for research and teaching, located in a new building with several laboratories fitted with modern equipment. SIPBS is unique in the UK and contains centres such as the Cancer Research UK Formulation Unit and CMAC. Staff from both these centres contribute to this course.

CMAC

CMAC is a world-class international hub for manufacturing research and training. Working in partnership with industry, its purpose is to transform current manufacturing processes into the medicine supply chain of the future.

Teaching staff

You'll be taught by experts from both SIPBS and CMAC. This course is multi-disciplinary and so specialised staff from other departments are also included. There are also specialised lectures from scientists from academia, industry, and public sector and partner organisations.

Future prospects

If you're interested in pursuing a PhD, this course is the perfect route in. It also gives you a range of skills and experience that employers from industry are looking for.

Course content

Compulsory classes

Generic Biomedical & Pharmaceutical Research Skills

To illustrate the many sources of scientific information available electronically, how to construct effective search protocols to find relevant information and present it using graphical means and oral presentations.

To enable you to understand, choose and use appropriate statistical methods to aid collection and interpretation of data in the biomedical and pharmaceutical sciences and associated industries.

To encourage you to engage in debate on:

  • scientific hypotheses
  • regulatory affairs & research funding
  • in vivo experimentation
  • human stem cell therapies

To introduce the concepts of:

  • skills evaluation and personal effectiveness
  • time management, planning and Gannt charts
  • decision-making processes and review
  • information and data management
  • good laboratory practice
  • peer interaction, communication and networking
  • preparing a CV, career planning and applying for future positions
Industrial Pharmacy

The aim of the class is to give advanced information on standard organics with highlighting the challenges on Biopharmaceuticals aspects in relation to drug development. It's focused on developing a rigorous understanding of pharmacy and pharmaceutical science as it is applied in an industrial setting including topic such as:

  • Stability and physicochemical principles
  • Pharmaceutical engineering
  • biotechnology and analysis
  • Standardisation of products
  • Pharmaceutical law and ethics
  • Thermodynamics and Kinetics
  • In vitro / In Vivo Correlation
  • Packaging materials and regulatory requirements
Process Analytical Technology & Quality by Design in Continuous Pharmaceutical Manufacturing

This class will also provide insight into the key principles of QbD covering quality risk management, formal experimental design and PAT, including topics such as: PAT tools and Implementation; PAT in Development and Manufacturing; Design of Experiments and Multivariate Data Analysis; Quality by Design (QbD)

Continuous Manufacturing of Pharmaceutical Particles & Products
This class aims to provide you with direct experience of continuous crystallisation and downstream processes. You'll have the opportunity to apply the underpinning knowledge gained from proceeding classes to manufacture a pharmaceutical product using continuous processes. It brings together several of the key scientific and engineering concepts introduced in other classes and culminates in the practical development and operation of continuous crystallisation, spray drying, extrusion and formulation steps. This class includes topic such as: Novel Pharmaceutical Particles and Fabrication Methods for different applications; Design processes for the formation of pharmaceutical particles; Continuous Processing and Crystallisation Technologies of Formulated Products ; Unit Operations for ‘end to end; continuous processing; Seeded cooling continuous crystallisation in Continuous Oscillatory Baffle Reactors (COBR) ; Application of in-line measurements (PAT) in a continuous process
Crystallisation & Formulation for Manufacture
The aim is to provide academic and practical training in drug and fine chemical crystallisation principles and the subsequent formulation and processing requirements to produce medicinal and consumer products. The areas covered include nucleation and crystallisation theories, the requirement for the medicinal and consumer products and the formulation of those products, including: Formulation and  pharmaceutical secondary processing techniques; granulation and tableting; physical characterisation of pharmaceutical; surface characterisation of crystalline material; Formulation, Manufacture & Testing.”
Pharmaceutical Project Management
The aim of this class is to impart knowledge and understanding of the Pharmaceutical Project management keeping in view of pharmaceutical, biotech and industry in mind. This class will provide you with the fundamentals of project management and show how to apply the principles of project management to a typical pharmaceutical project, including topic such as: Pharmaceutical R&D and Business Processes; Project Planning; Project Management of Chemical, Analytical, and Formulation Development; Operations management, Processes and production; Marketing & Entrepreneurship”

MSc only

Continuous Manufacturing Research Project
You'll undertake an assignment usually in one of the continuous manufacturing and crystallisation research laboratories where they undertake a project and prepare a thesis for assessment.

Learning & teaching

Theory and applications are taught through lectures, tutorials, seminars and web-based learning. Class material is available through an online learning tool which you can access at any time.

You’ll also take part in practical sessions which provide you with experience of a wide range of modern instrumental and state-of-the-art techniques.

Assessment

Assessment is through both written and practical examinations and submission of a thesis (MSc students only).

Entry requirements

  • minimum second-class Honours degree (or equivalent qualification) in science or engineering
  • two references (at least one academic)
  • English language: minimum IELTS 6.5 is required for all non-English speakers

Fees & funding

2018/19

All fees quoted are for full-time courses and per academic year unless stated otherwise.

Scotland/EU

  • £7,800

Rest of UK

  • £7,800

International

  • £18,750

How can I fund my course?

Scottish and non-UK EU postgraduate students

Scottish and non-UK EU postgraduate students starting in 2017 may be able to apply for support from the Student Awards Agency Scotland (SAAS). The support is in the form of a tuition fee loan and for eligible students a living cost loan. Find out more about the support and how to apply.

Don’t forget to check our scholarship search for more help with fees and funding.

Students coming from England

Students ordinarily resident in England can apply for Postgraduate support from Student Finance England. The support is a loan of up to £10,280 which can be used for both tuition fees and living costs. Find out more about the support and how to apply.

Don’t forget to check our scholarship search for more help with fees and funding.

Students coming from Wales

Postgraduate students starting in 2017 who are ordinarily resident in Wales can apply for support from Student Finance Wales. The support is a loan of up to £10,280 which can be used for both tuition fees and living costs. We are waiting on further information being released about this support and how to apply.

Don’t forget to check our scholarship search for more help with fees and funding.

Students coming from Northern Ireland

Postgraduate students starting in 2017 who are ordinarily resident in Northern Ireland can apply for support from Student Finance NI. The support is a tuition fee loan of up to £5,500. We are waiting on further information being released about this support and how to apply.

Don’t forget to check our scholarship search for more help with fees and funding.

International students

We have a large range of scholarships available to help you fund your studies. Check our scholarship search for more help with fees and funding.

Please note

The fees shown are annual and may be subject to an increase each year. Find out more about fees.

Careers

The course prepares you for a career in:

  • the chemical or pharmaceutical industry (research and development, production and regulatory affairs)
  • academic and other research institutions
  • government agencies such as drug licensing authorities

You’ll also be equipped to continue into PhD research at one of the University’s Doctoral Training Centres.

Recent graduates form this course have gained posts in GSK and Sigma-Aldrich FC.

Contact us

Apply

Please complete the online application form. The following documents (PDF files only) are requested:

  • degree certificate(s)
  • two references (at least one academic)
  • English language certificate
  • passport copy

Advanced Pharmaceutical Manufacturing

Qualification: MSc, Start date: Sep 2018, Mode of delivery: attendance, part-time

Advanced Pharmaceutical Manufacturing

Qualification: MSc, Start date: Sep 2018, Mode of delivery: attendance, full-time

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