PhD, MPhil Pharmacy & biomedical sciences

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Sex difference in right ventricular fibrosis in pulmonary arterial hypertension

More females develop pulmonary arterial hypertension (PAH) than males. However, female PAH patients have better right ventricular (RV) function including less fibrosis and as a result better survival than the males. The mechanism for the sex-dependent RV fibrosis is not well studied and this project will investigate the underlying mechanism to gain better knowledge and develop therapeutic strategies for PAH.

Deadline:

Funding:

unfunded




Co-producing a Common Clinical Conditions service in the Scottish Prison Service

People within prison services have a poor record of health and experience profound health inequalities. The prison population have significant disadvantages including poor health literacy. In general society people with poor health literacy experience worse health outcomes than normal and find it challenging to navigate health systems. This PhD will focus on co-designing a service that enables people within prisons to work with healthcare professionals to manage their common clinical conditions.

Deadline:

Funding:

unfunded

Identification of novel therapies targeting the right ventricle in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a fatal, rapidly progressive disease, leading to right ventricular (RV) failure and death. Though the pathology in PAH begins with an obstructive vasculopathy in the lungs, the prognosis is mainly determined by RV function. However, there is no effective drug directly targeting the RV. This project will identify novel therapeutic targets for RV in PAH using both animal model, clinical samples and a range of metabolomics and proteomics technologies.

Deadline:

22 June 2024

Funding:

funded








Rethinking Women’s Health: Improving the management of endometriosis and addressing unmet support needs

Women’s health is a chronically under-researched area despite the fact that slightly more than half of the global population is female. Our understanding of several conditions primarily or exclusively affecting female patients – including endometriosis, which can have a profound impact on women’s well-being – is insufficient, and disease symptoms are frequently trivialised. Consequently, there is a substantial need to improve how patients are supported in their daily lives.

Deadline:

Funding:

unfunded





Anti-cancer cardiotoxicity and metabolic mechanisms in healthy and diseased hearts

Aims of the project: Does anti-cancer therapy result in dysfunction at the level of both contractile and non-contractile cells of the heart? Are cardio-compromised hearts more susceptible to the effects of these drugs? Are there specific metabolic profiles associated with anti-cancer drug treated cardiac cells that would allow identification of early onset biomarkers of cardiotoxicity?

Deadline:

Funding:

unfunded



Is the cholesterol intracellular transport pathway a potential therapeutic target for glioblastoma?

Glioblastoma is a lethal brain tumour with a worldwide incidence of ~5 per 100,000 persons and <5% five-year survival. We have identified a cholesterol intracellular transport gene signature in glioblastoma that correlates with worse prognosis. The proposed project aims to investigate the potential of targeting the cholesterol intracellular transport pathway as a novel target for therapeutic intervention in this cancer of unmet need.

Deadline:

Funding:

unfunded

Using the electronic frailty index (eFI) to redefine deprescribing in Scotland

The electronic Frailty Index (eFI) has been developed to identify frailty within general practice settings. Pilot studies on 900,000 individuals in England have demonstrated that the eFI is simple and quick to use and is able to discriminate older patients referred for comprehensive geriatric assessment. But in Scotland the eFI has not been adopted in the same way and this project aims to map out the reasons why and determine its use in helping to deprescribe medicines within the elderly.

Deadline:

31 July 2024

Funding:

funded







John Anderson Research Studentship Scheme (JARSS)

John Anderson Research Studentship Scheme (JARSS) doctoral studentships are available annually for excellent students and excellent research projects.

There are two main sources of funding:

  • Central University funding
  • Engineering and Physical Sciences Research Council - Doctoral Training Partnership (EPSRC - DTP) funding.

The JARSS 2023/2024 competition will open in October 2023 and students successful in this competition will commence studies in October 2024. Faculties will set their own internal deadlines for the competition.

Academics/Supervisors make the applications for this scheme and there are various deadlines across the Department and Faculties, therefore, in the first instance, all interested students should contact the Department where they would like to carry out their research.

Deadline:

Funding:

Funded

THE Awards 2019: UK University of the Year Winner
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Fees & funding

All fees quoted are per academic year unless otherwise stated.

Entrants may be subject to a small fee during the writing up period.

Fees may be subject to updates to maintain accuracy. Tuition fees will be notified in your offer letter.

All fees are in £ sterling, unless otherwise stated, and may be subject to revision.

Annual revision of fees

Students on programmes of study of more than one year (or studying standalone modules) should be aware that tuition fees are revised annually and may increase in subsequent years of study. Annual increases will generally reflect UK inflation rates and increases to programme delivery costs.

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Scotland

£4,786

England, Wales & Northern Ireland

£4,786

International

TBC

Funding

Take a look at our funding your postgraduate research web page for funding information.

You can also view our scholarships search for further funding opportunities.

Postgraduate research opportunities

Search for all funded and non-funded postgraduate research opportunities.

Additional costs
  • lab coats and safety goggles approx £25
  • cost of binding two copies of thesis and a CD copy £25 per each thesis

International students

International students may have associated visa and immigration costs. Please see student visa guidance for more information.

Please note: the fees shown are annual and may be subject to an increase each year. Find out more about fees.

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Supervisors

NameResearch methodologies & approaches usedCurrent PhD student topics
Professor Hannah Batchelor

biopharmaceutics, dissolution, caco-2 cells, permeability, pharmaceutical oral dosage form manufacture and characterisation.

  • understanding the impact of the gut lumenal conditions on tablet performance
  • using advanced physiologically relevant dissolution testing to understand the performance of oral medicines
  • generating biorelevant dissolution methods for special populations (eg paediatrics)
Dr Cameron Brown 

pharmaceutical manufacturing (small molecule drug substance, crystallisation), process modelling, physics-based, data-driven and hybrid modelling approaches.

  • material sparing approaches for the exploration of chemical space for optimum  process development
Dr Trevor Bushell

calcium imaging, electrophysiology, immunofluorescence, molecular biology, behavioural testing.

  • Is PAR2 activation neuroprotective in a mouse model of Alzheimer’s Disease
  • Targeting astrocytes as a novel treatment for CNS disorders.         
  • Does astrocytic PAR2 contribute to major depressive disorder?
Dr Susan Chalmers 

fluorescence imaging (live-cell) - mitochondrial dynamics & function; calcium signalling; immunofluorescence; image analysis & quantification.

  • How does the Alzheimer's associated amyloid-beta affect mitochondrial dynamics & function in neurons & astrocytes?
  • Does hyper- or hypo-glycaemia alter mitochondrial dynamics in cells of the CNS?
  • Ketone-body metabolic supplementation: a potential neuroprotective strategy?
Dr Luke Chamberlain 

a range of biochemical and cell biology approaches including: gel electrophoresis, immunoblotting, cell culture and transfection, click chemistry, confocal microscopy, inhibitor screening. 

  • Understanding how the attachment of lipid groups onto proteins affects their intracellular localisation, stability and function.
  • Understanding how defects in protein lipidation cause disease.
  • Identifying mechanisms underpinning substrate recognition by "ZDHHC" enzymes.
Dr Hilary Carswell 

In vivo models of brain injury and behavioural testing, in vitro cell culture and stem cell biology, molecular biology, histology including immunofluorescence.

  • improving stem cell function in stroke
  • using biomaterials to improve stroke recovery
  • immunomodulatory therapies in stroke
  • exploring therapies that target the blood brain barrier and inflammation in stroke
  • developing and improving in vitro models of stroke
Dr Christine Dufès 

development of novel tumour-targeted nanomedicines for cancer therapy (synthesis and characterization of the nanomedicines, cell culture, flow cytometry, anti-proliferative assay, confocal microscopy, in vivo analysis)

  • development of tumour-targeted drug and gene nanomedicines for cancer therapy
  • development of non-viral CRISPR-Cas9 technologies
  • tumour microenvironment-sensitive drug and gene delivery systems
  • biomaterial-based immunotherapies
  • development of novel hydrogels for biomedical applications
  • brain-targeted drug and gene delivery systems
Dr Ru Angelie Edrada-Ebel 

Natural Products Metabolomics, Co-culture applications on Marine Biotechnology, NMR Spectroscopy, Mass Spectrometry, High-throughput Chromatography, application of multivariate analysis on fused spectral data.

  • understanding the effects of cocultures on microbial symbionts to elicit the production of new antibiofilms and antibiofoulants
  • algal endophytes on biofilms and biofoulants
  • multivariate analysis of fused spectral datasets to model metabolite production in various ecological conditions
Dr Hui-Rong Jiang 

in vivo models of neuroinflammation (multiple sclerosis and Alzheimer's disease), cell culture, molecular biology, immunoassays,  immunohistochemical staining and imaging, application of nanoclusters

  • understanding neuroinflammation in neurodegenerative disease
  • developing novel therapies for Alzheimer's disease using lysozyme encapsulated nanoclusters
  • role of immune molecules in cancer development
Dr Amanj Kurdi  clinical pharmacy, pharmacoepidemiology, pharmacy practice 
  • application of pharmacoepidemiological approaches to investigate the utilisation pattern
  • clinical effectiveness
  • safety of the novel medications used in the management of cardiovascular diseases
Dr Helina Marshall 

bacteriology, Immunology, flow cytometry, molecular biology, microscopy, cell-based assays

  • understanding the immune evasion mechanisms of atypical emerging strains of Salmonella and how they are continuing to adapt to their host
  • determining the mechanisms of differential virulence of related species of Streptococcus, and aiming to understand what makes a pathogen
Professor Gail McConnell

optical microscopy and mesoscopy development, applications of new imaging technologies to cell biology and medicine

  • resolving the role of microbial pathogens in the failure of voice prosthetic devices
  • quantification of immune markers in tonsillar diseases
  • label-free intraoperative histological imaging
  • super-resolution optical mesoscopy
  • understanding the ultrastructure of mature colony biofilms
Dr Iain Oswald

diffraction and spectroscopic methodologies under various thermodynamic regimes to explore the solid-state properties of active pharmaceutical ingredients.

  • linking molecular structure to mechanical properties of pharmaceutical materials
Professor Yvonne Perrie

drug delivery, delivery of drugs and vaccines, liposomes, nanoparticles

  • development of novel particulate delivery systems for mRNA therapies
  • enhancing microfluidic manufacturing processes for nanoparticles
  • developing novel subunit vaccine formulations
Dr Leighton Pritchard 

computational biology, bioinformatics, systems biology, microbial genomics

 

Dr Nicholas JW Rattray 

metabolomics, proteomics, hyphenated mass spectrometry, biogerontology (biochemistry of ageing), clinical trails, clinical sample handling, biobanking, chemometrics, AI and deep learning

  • developing novel multiparametric measures of ageing in clinical/biomolecular biobank data
  • determining new mass spectrometry methods of mitochondrial screening
  • translating biomolecular signatures of frailty into clinically relevant biomarkers
Dr Zahra Rattray

biologicals, nanomedicine, cell-based assays, advanced metrology techniques, cell culture, immunoblotting, imaging and image analysis

  • understanding how lipid chemistry alters lipid nanoparticle critical quality attributes and their in vitro behaviour
  • understanding the phenotypic properties of breast cancer cells with Karyopherin alpha 2 knockdown
  • understanding the immunometabolic profile of immune cells in response to nanomaterials
Dr Shuzo Sakata

in vivo electrophysiology (including Neuropixels), fibre photometry, optogenetics, chemogenetics, viral-based gene delivery, deep learning

  • sleep-stage-dependent functions of pontine waves
  • REM sleep regulation by pontine neuron-astrocyte interactions
  • optical detection of Alzheimer's pathology in vivo
  • deficits in experience-dependent sharp-wave ripples in an Alzheimer's mouse model
Dr Veronique Seidel

molecular docking, molecular dynamics, cell-based assays, chromatography and spectroscopy techniques applied to natural products research 

  • studies on the role of medicinal plant extracts and compounds in skin health using in silico and in vitro screening
Dr Lian Tian

in vivo animal experiments, ex vivo tissue measurement, in vitro cell culture and biological approaches

  • Novel therapies targeting the right ventricle in pulmonary arterial hypertension
Dr Martin Wiese

molecular parasitology and biochemistry, leishmania protein kinases

  • CRISPR-Cas9
  • molecular biology
  • protein biochemistry
  • cell biology
  • microscopy
  • proximity labelling (BioID).

 

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Support & development

Postgraduate Certificate in Researcher Professional Development (PgCert RPD)

As part of your PhD degree, you'll be enrolled on the Postgraduate Certificate in Researcher Professional Development (PgCert RPD). 

This certificate is designed to support you with your research and rewards you for things you'll do as a research student here.

It'll help you improve skills which are important to professional development and employability:

  • knowledge and intellectual abilities to conduct your research
  • personal qualities to succeed in your research and chosen career
  • standards, requirements and conduct of a professional researcher in your discipline
  • working with others and communicating the impact of your research to a wide range of audiences

All you have to do is plan these activities alongside your doctorate, documenting and reflecting your journey to success along the way.

Find out more about the PgCert RPD programme.

Careers

The University Careers Service can help you with everything from writing your CV to interview preparation.

Student support

From financial advice to our IT facilities, we have a wide range of support for all students here at Strathclyde. Get all the information you need at Strathlife.

Postgraduate research at the Strathclyde Doctoral School

The Strathclyde Doctoral School provides a vibrant and comprehensive student-centred research and training environment in order to grow and support current and future research talent.

The School encompasses our four faculties and is committed to enriching the student experience, intensifying research outputs and opportunities, and ensuring training is at the highest level. As a postgraduate researcher, you'll automatically become a member of the Strathclyde Doctoral School.

Find out more about the Doctoral School

Meet our people

Margaret Cunningham

Margaret Cunningham

Senior Lecturer

I am a pharmacologist at SPBS where my research group focuses upon understanding the molecular level mechanisms of cardiovascular dysfunction. In addition to being a scientist, I am a mother of three, rugby enthusiast and dabble as an artist on the side. My recent art project involves painting rocks with STEM themes.
Zahra Rattray

Zahra Rattray

Senior Lecturer

As the sister of a cancer survivor, I developed a passion for discovering new treatments in the fight against cancer. Fast forward to the present day, I have started my independent research career investigating ways to improve how cancer treatments target and reach tumours. I am passionate about sharing science with people from all walks of life and inspiring the next generation of scientists.

International students

We've a thriving international community with students coming here to study from over 140 countries across the world. Find out all you need to know about studying in Glasgow at Strathclyde and hear from students about their experiences.

Visit our international students' section

Dr Paul Hoskisson

Paul Hoskisson

Professor in Molecular Microbiology

I'm a microbiologist/biochemist who works on antibiotic-producing bacteria with a view to combatting the antimicrobial resistance crisis we are facing. We also work on pathogenic bacteria and on exploiting frog proteins as drugs. Outside of my science I can normally be found in a pond or rainforest around the world trying to photograph frogs, snakes and lizards or watching cricket!
Professor Robin Plevin

Robert Plevin

Head of Institute

I have a passion for pharmacology and understanding how new drugs can be applied to diseases such as cancer, inflammation and heart disease. Outside my research, I spend time coaching the over 55s Scotland Hockey team to limited success (we always lose to the good teams!). I love writing poetry and have participated recently in a Poetry and leadership conference.
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Apply

Entry requirements

Upper second-class UK Honours degree or overseas equivalent.

The application

During the application you'll be asked for the following:

  • your full contact details
  • transcripts and certificates of all degrees
  • proof of English language proficiency if English isn't your first language
  • two references, one of which must be academic
  • funding or scholarship information
  • research proposal of 250 to 1,000 words in length, detailing the subject area and topic to be investigated

By filling these details out as fully as possible, you'll avoid any delay to your application being processed by the University.

International applicants

If you're applying as an international student, you'll need to provide:

  • proof of IELTS English language proficiency – score of 6.5, with no element below 5.5 – if English isn't your first language
  • a scanned copy of your passport
  • a copy of your funding letter, if available

By filling these details out as fully as possible, you'll avoid any delay to your application being processed by the University.

Supervisors

Research supervisors are assigned to you by the Strathclyde Institute of Pharmacy & Biomedical Sciences. Let us know in your application who you'd like to work with, but the department will team you up with the best supervisor for your project.

Once we've received your application, your research proposal is passed to potential supervisors for consideration. If it's not compatible with the researcher's current projects and they are unable to supervise, it's passed along to another for consideration. If they can supervise you, they’ll confirm and nominate a potential second supervisor. As soon as a second supervisor is confirmed, an offer will be sent to you through Pegasus, our online application system.

When you accept our offer of study, you'll receive a full offer in writing via the email address you'll have provided.

Accepting an offer

When you've accepted our offer, we'll need you to fulfil any academic, administrative or financial conditions that we ask.

UK or EU students

If you're applying as a UK or EU student, you'll then be issued with your registration documentation.

International students

An ATAS (Academic Technology Approval Scheme) clearance certificate is a mandatory requirement for some postgraduate students in science, engineering and technology.

Find out if you need an ATAS certificate.

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy)

PhD
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy) - Plus

PhD
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy) - Plus

PhD
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy)

PhD
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy)

MPhil
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Pharmacy)

MPhil
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences)

PhD
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences) - Plus

PhD
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences) - Plus

PhD
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences)

PhD
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences)

MPhil
full-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2023 - Sep 2024

SIPBS (Biomedical Sciences)

MPhil
part-time
Start date: Oct 2023 - Sep 2024

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy)

PhD
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy) - Plus

PhD
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy) - Plus

PhD
part-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy)

PhD
part-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy)

MPhil
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Pharmacy)

MPhil
part-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences)

PhD
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences) - Plus

PhD
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences) - Plus

PhD
part-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences)

PhD
part-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences)

MPhil
full-time
Start date: Oct 2024 - Sep 2025

Start date: Oct 2024 - Sep 2025

SIPBS (Biomedical Sciences)

MPhil
part-time
Start date: Oct 2024 - Sep 2025

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Contact us

Pharmacy & biomedical sciences

Telephone: +44 (0)141 548 2135

Email: sipbs-postgrad@strath.ac.uk