Dr Rebecca Beveridge

Senior Lecturer

Pure and Applied Chemistry

Personal statement

Rebecca is a Senior Lecturer and UKRI Future Leaders Fellow who joined the University of Strathclyde in June 2020 as a Chancellor's Fellow. She obtained a BSc in biochemistry and chemistry from the University of Leeds in 2011 and completed her PhD at the University of Manchester in 2015. Rebecca spent 4 years at the Institute for Molecular Pathology in Vienna, Austria as a postdoctoral researcher/ Lise Meitner Postdoctoral Fellow. Throughout her career, she has collected experience in a plethora of mass spectrometry methods to study protein structure such as native mass spectrometry, ion mobility, hydrogen-deuterium exchange, and crosslinking.

Rebecca’s current research is centered around the development of native ion mobility mass spectrometry methods to study proteins and protein complexes, particularly those that are challenging to study with conventional biochemistry methods. Such systems include intrinsically disordered proteins that exist in a wide range of different shapes, and protein complexes formed by protein-degrading molecules such as PROTACs, the complex binding modes of which are challenging to delineate.

Expertise

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Prize And Awards

2025 RSC Analytical Division Joseph Black Award for Early Career Researchers: Recipient; 25/6/2025

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Publications

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Publications

Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor: Ahmed Ikhlas M M, Rofe Adam, Henry Martyn C, West Eric, Jamieson Craig, McEwan Iain J, Beveridge Rebecca; Protein Science Vol 34 (2025); https://doi.org/10.1002/pro.5254
S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents: Perieteanu Marina, Rodriguez Garzon Tayner, McGee Leah M C, Khalaf Abedawn I, Suckling Colin J, Beveridge Rebecca, Avery Vicky M, Scott Fraser J; RSC Medicinal Chemistry Vol 16, pp. 412-419 (2025); https://doi.org/10.1039/D4MD00619D
Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii: McGee Leah MC, Carpinteyro Sanchez Alemao G, Perieteanu Marina, Eskandari Kaveh, Bian Yan, Mackie Logan, Young Louise, Beveridge Rebecca, Suckling Colin J, Roberts Craig W, Scott Fraser J; Journal of Antimicrobial Chemotherapy Vol 79, pp. 2251-2258 (2024); https://doi.org/10.1093/jac/dkae221
Amorphous aggregates with a very wide size distribution play a central role in crystal nucleation: Liao Zhiyu, Das Ankita, Robb Christina Glen, Beveridge Rebecca, Wynne Klaas; Chemical Science Vol 15, pp. 12420-12430 (2024); https://doi.org/10.1039/D4SC00452C
Rapid flow-based synthesis of post-translationally modified peptides and proteins : a case study on MYC's transactivation domain: Williams Elyse T, Schiefelbein Kevin, Schuster Matthias, Ahmed Ikhlas M M, De vries Marije, Beveridge Rebecca, Zerbe Oliver, Hartrampf Nina; Chemical Science Vol 15, pp. 8756-8765 (2024); https://doi.org/10.1039/D4SC00481G
Exploiting bi-specific engagement : assessing monovalent vs bivalent binding: Duxbury Rachel, Beveridge Rebecca, Jamieson Craig, Jones David, Jones Gavin, Rattray Zahra; Immuno-oncology Summit Europe 2024 (2024)

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Research

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Professional Activities

Native mass spectrometry analysis of complexes formed by protein degraders: Speaker; 24/7/2025
Ion mobility mass spectrometry unveils global protein conformations in response to conditions that promote and reverse liquid-liquid phase separation: Speaker; 22/7/2025
Native Mass Spectrometry Analysis of Complexes Formed by Protein Degraders: Speaker; 4/12/2024
Native mass spectrometry analysis of complexes formed by protein degraders: Speaker; 15/11/2024
Symposium for Structural Proteomics: Participant; 28/10/2024
British Mass Spectrometry Biomacromolecular SIG meeting: Participant; 25/10/2024

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Projects

An integrated analysis of S-acylation dynamics and its importance in cell physiology (APP4861): Chamberlain, Luke (Principal Investigator) Beveridge, Rebecca (Co-investigator) Tomkinson, Nick (Co-investigator); 01-Jan-2025 - 30-Jan-2030
A Prosperity Partnership for the Design, Synthesis, and Evaluation of Next Generation Molecules Beyond Lipinski Space: Jamieson, Craig (Principal Investigator) Beveridge, Rebecca (Co-investigator) Burley, Glenn (Co-investigator) Kerr, William (Co-investigator) Lindsay, David (Co-investigator) Palmer, David (Co-investigator) Tomkinson, Nick (Co-investigator); 01-Jan-2025 - 31-Jan-2030
Native MS of pyrenoid components: Beveridge, Rebecca (Principal Investigator); 17-Jan-2025 - 21-Jan-2025
Understanding intrinsically disordered proteins and their potential as new drug (FLF renewal): Beveridge, Rebecca (Principal Investigator); 01-Jan-2024 - 31-Jan-2027
DTP 2224 University of Strathclyde | Madoda, Mxolisi: Beveridge, Rebecca (Principal Investigator) Chow, Shiao (Co-investigator) Madoda, Mxolisi (Research Co-investigator); 01-Jan-2023 - 01-Jan-2027
Intact protein mass measurement: Beveridge, Rebecca (Principal Investigator); 01-Jan-2023 - 31-Jan-2024