Publications

Total normal curvature regularization and its minimization for surface and image smoothing

Lu Tianle, Chen Ke, Duan Yuping

SIAM Journal on Imaging Sciences Vol 19, pp. 879-912 (2026)

https://doi.org/10.1137/25m1782613

Fast augmented Lagrangian primal dual algorithm for mean curvature regularization model

Lu Tianle, Zhang Jianping, Duan Yuping, Chen Ke

Journal of Mathematical Imaging and Vision Vol 68 (2026)

https://doi.org/10.1007/s10851-026-01304-x

An effective deep learning algorithm for medical image registration

Deng Jinqiu, Chen (Ken), Li Mingke, Frangi Alejandro F, Zhang Jianping

PLOS Digital Health Vol 5 (2026)

https://doi.org/10.1371/journal.pdig.0001339

Graph-based inhomogeneity image segmentation with the optimal transport metric

Huang Jisui, Chen Ke, Alpers Andreas, Lei Na

2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp. 6700-6707 (2026)

https://doi.org/10.1109/bibm66473.2025.11357138

A novel few-shot learning framework for supervised diffeomorphic image registration network

Chen Ke, Han Huan, Wei Junping, Zhang Yimin

IEEE Transactions on Medical Imaging Vol 44, pp. 4903-4917 (2025)

https://doi.org/10.1109/TMI.2025.3585199

A new and efficient fixed point method for mean curvature denoising model

Yang Fenlin, Zhang Jianping, Zhang Jin, Chen Ke

International Journal of Computer Mathematics Vol 102, pp. 1865-1879 (2025)

https://doi.org/10.1080/00207160.2025.2517271

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Professional Activities

Invited talk

Speaker

17/12/2026

PhD exam Edinburgh

Examiner

12/6/2026

Modern Optimisation Techniques and Deep Learning

Organiser

29/5/2026

PhD Exam Leeds

Examiner

16/5/2026

PhD exam Dundee

Examiner

1/5/2026

21st International Conference on Computer Vision Theory and Applications (VISAPP 2026) (Event)

Peer reviewer

9/3/2026

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Projects

Synergistic integration of deep learning and mathematical modelling to characterise CAR-T cell dynamics and therapeutic outcomes in the TNBC micro-environment (International Exchange Cost Share NSFC)

Wu, Yue (Principal Investigator) Chen, Ke (Co-investigator) Rattray, Nicholas (Co-investigator)

01-Jan-2026 - 31-Jan-2027

Spatial omics using histology, mass spectrometry imaging and spatial transcriptomics to investigate metabolites across tissue regions

Chen, Ke (Principal Investigator)

30-Jan-2024 - 29-Jan-2027

Centre for Mathematical Sciences in Healthcare

Chen, Ke (Principal Investigator)

£6M grant awarded for 2015-2021 (£2.5M EPSRC and Rest from Partners)

01-Jan-2015 - 30-Jan-2021

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