Dr Carsten Schulte
Strathclyde Chancellor's Fellow
Biomedical Engineering
Personal statement
Personal statement
The major interest of my research has always been the amazing interaction of cells with their surrounding microenvironment. Within this framework, my main lines of research aim to understand how the force-based dialogue between the cell and the extracellular matrix affects the mechanobiology, signalling and function of the cell. In particular, I am fascinated by the complex molecular mechanotransductive mechanisms that translate biophysical microenvironmental information (e.g., nanotopography) into cellular responses with drastic morphological and functional changes and how this contributes to (patho)physiological situations, such as cellular differentiation and cancer.
To this end, I implement highly interdisciplinary approaches and combine versatile state-of-the-art techniques from various fields such as cell biology, mechanobiology, advanced imaging, engineering (biomaterials), biophysics, pharmacology, nanotechnology, omics and biochemistry.
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Prize And Awards
- Associate Fellow of the Higher Education Academy
- Recipient
- 2026
- Strathclyde Chancellor's Fellow
- Recipient
- 10/6/2024
- Postdoctoral fellowship - IFOM
- Recipient
- 1/9/2008
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Publications
- The glycocalyx affects the mechanotransductive perception of the topographical microenvironment
- Chighizola Matteo, Dini Tania, Marcotti Stefania, D’Urso Mirko, Piazzoni Claudio, Borghi Francesca, Previdi Anita, Ceriani Laura, Folliero Claudia, Stramer Brian, Lenardi Cristina, Milani Paolo, Podestà Alessandro, Schulte Carsten
- Journal of Nanobiotechnology Vol 20 (2022)
- https://doi.org/10.1186/s12951-022-01585-5
- Mechanotransduction in stem cells
- Ferrai Carmelo, Schulte Carsten
- European Journal of Cell Biology Vol 103 (2024)
- https://doi.org/10.1016/j.ejcb.2024.151417
- The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A
- Gohar Yomna, Kalogerakou Eirini, Akyel Matthias, Kumar Priya, Darna Margarita, Stitzinger Simon H, Gottwald Jannis, Kaplani Konstantina, Piazzoni Claudio, Du Manyu, Janshoff Andreas, Cisse' Ibrahim I, Fornasiero Eugenio F, Milani Paolo, Papantonis Argyris, Schulte Carsten, Ferrai Carmelo
- (2026)
- https://doi.org/10.64898/2026.02.12.705261
- A tour de force through cellular nanoscale mechanobiology in (patho)physiology
- Schulte Carsten
- CellMech2025 (2025)
- Impact of endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) on neutrophil cellular functions
- Saulle Irma, Limanaqi Fiona, Garziano Micaela, Murno Maria Luisa, Artusa Valentina, Strizzi Sergio, Giovarelli Matteo, Schulte Carsten, Aiello Jacopo, Clerici Mario, Vanetti Claudia, Biasin Mara
- Frontiers in Cell and Developmental Biology Vol 12 (2025)
- https://doi.org/10.3389/fcell.2024.1506216
- Native extracellular matrix probes to target patient- and tissue-specific cell-microenvironment interactions by force spectroscopy
- Holuigue H, Nacci L, Di Chiaro P, Chighizola M, Locatelli I, Schulte C, Alfano M, Diaferia G R, Podestà A
- Nanoscale Vol 15, pp. 15382-15395 (2023)
- https://doi.org/10.1039/d3nr01568h
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Professional Activities
- 6th International Symposium for Mechanobiology (ISMB) 2026
- Chair
- 15/7/2026
- CeMi Round Table @BME
- Organiser
- 11/2/2026
- A Tour de Force through Mechanobiology in Health and Disease
- Speaker
- 3/12/2025
- BME Seminar
- Organiser
- 12/2025
- Joint Forum 2025: Scotland x Lower Saxony
- Participant
- 27/11/2025
- A mechanobiological perspective on glioblastoma pathophysiology
- Speaker
- 18/11/2025
Projects
- Breaking the code of inflammation: How cells sense and respond to physical signals
- Brennan, Lucy (Post Grad Student) Pineda, Miguel (Principal Investigator) Schulte, Carsten (Principal Investigator) Gadegaard, Nikolaj (Principal Investigator)
- PhD studentship supervised (40%) by Dr Carsten Schulte in collaboration with Dr Miguel Pineda (40%, first supervisor) and Prof Nikolaj Gadegaard (20%) (both, University of Glasgow) through the BBSRC-funded
Doctoral Training Partnership NorthWestBio. - 01-Jan-2025 - 31-Jan-2029
- Exploring the roles of myosin VI in mechanotransduction
- Schulte, Carsten (Principal Investigator) Wollscheid, Hans-Peter (Principal Investigator) Fowler, Dylan (Post Grad Student) Stiehler, Felizitas (Post Grad Student)
- Research exchange project funded by the Rheinland-Pfalz & Scotland x Life Sciences Fund jointly awarded by JGU Scotland HUB and SULSA - Scottish Universities Life Sciences Alliance, sponsored by the Ministerium für Wissenschaft und Gesundheit Rheinland-Pfalz and The Scottish Government!
- 08-Jan-2025 - 31-Jan-2025
- Harnessing interdisciplinary mechanobiological characterisations of medulloblastoma as prompt for novel therapeutic approaches
- Schulte, Carsten (Principal Investigator)
- 01-Jan-2025 - 31-Jan-2027
- Geometries of Migration: Glioblastoma Cell Dynamics in Microconfinement
- Witte, Kimia (Principal Investigator) Schulte, Carsten (Co-investigator) Merrett, Lorna (Research Co-investigator) Fowler, Dylan (Research Co-investigator)
- John Gaylor Collaboration Fund (JGCF) 2025
- 01-Jan-2025 - 31-Jan-2026
- Leveraging mechanobiology for the optimisation of in vitro muscle-related disease models
- Schulte, Carsten (Principal Investigator) Sandison, Mairi (Co-investigator)
- 01-Jan-2025 - 31-Jan-2026
- DTP 2224 University of Strathclyde | Fowler, Dylan
- Schulte, Carsten (Principal Investigator) Reid, Stuart (Co-investigator) Fowler, Dylan (Research Co-investigator)
- 01-Jan-2024 - 01-Jan-2028
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Contact
Dr
Carsten
Schulte
Strathclyde Chancellor's Fellow
Biomedical Engineering
Email: carsten.schulte@strath.ac.uk
Tel: Unlisted