Professor David Birch

Emeritus Professor

Physics

Personal statement

David Birch leads the Photophysics Group and works with fluorescence to address interdisciplinary molecular grand challenges at the biomedical interface that are relevant to metabolism and disease. The Group has raised many millions in research funding and successfully trained over 70 research students and post-doctoral fellows, 7 later becoming full professors and others leaders of industry.

David gained early industrial experience working in mass spectrometry with VG Micromass. He is one of the pioneers of modern-day fluorescence lifetime spectroscopy and a driving force that has helped make Scotland their global manufacturing hub. For his PhD at Manchester University David designed and built a novel time-correlated single-photon timing (TCSPC) fluorescence lifetime instrument and subsequently converted it into world-leading products through IBH, the company he co-founded in 1977 as one of the first Scottish University spin-out companies. Subsequently he successfully bridged the Industry-University divide for over 40 years as a Company Director and Academic. As part of HORIBA IBH is now the market-leader in fluorescence spectroscopy. In 2019 IBH was awarded the Institute of Physics Business Innovation Award for the development of the FLIMera multiplexed TCSPC molecular movie camera capable of 25,000 simultaneous TCSPC measurements.  

David's innovations in measurement are contributing to a wide range of applications, many of critical importance in understanding the molecular science which underpins healthcare. His present research is focused on biomolecular structure and dynamics down to the single molecule level; melanin structure, photophysics and melanoma; fluorescence guided surgery, glucose sensing for diabetes; aggregation leading to fibrils e.g. beta-amyloid and Alzheimer’s disease; gold nanoparticle photophysics and its application to sensing, imaging and fluid biopsy; and 1-10 nm nanoparticle metrology. A list of David's publications is available. 

David is a Fellow of Scotland's National Academy, the Royal Society of Edinburgh, a Founding Director of HORIBA Jobin Yvon IBH Ltd and the Visiting Professor of Applied Physics at the Czech Technical University in Prague. He held the Sir C V Raman Endowment Chair at the University of Madras in 1998-99 and previously research fellowships from the Royal Society, the Nuffield Foundation and the Japanese Society for the Promotion of Science. In 2014 he was appointed to the Green Honors Chair in Physics at Texas Christian University in Fort Worth. In 2017 he received the HORIBA Lifetime Achievement Award for 40 years of innovation in time-correlated single-photon counting.

He was Editor-in-Chief of Measurement Science and Technology from 2012-2016 and led the journal to its highest impact factor since it was launched in 1923 as the world's first measurement journal and the first research journal produced by the Institute of Physics. Presently he is co-founding Editor-in-Chief of Methods and Applications in Fluorescence, one of the Institute's newest journals. He was a member of the Editorial Board of SPIE's Journal of Biomedical Optics from its launch in 1996 until 2019. David served as Head of Department from 2004-10, a period building up to and including 2.5 years of the Government-led REF 2014 assessment from which the Times Higher Education ranked Strathclyde as the number one in the UK for Physics Research.

David convened the session on Photochemistry, Photophysics and Electrochemistry at the 7th EuCheMS Congress in Liverpool in August 2018. He launched the FluoroFest Series of International Workshops in Prague in 2009 and Chaired the 12th FluoroFest held in Glasgow in 2017. The latest in the series was held in Fort Worth in May 2019.

 

Publications

A rapid analysis platform for investigating the cellular locations of bacteria using two-photon fluorescence lifetime imaging microscopy
Sapermsap Natakorn, Li David Day-Uei, Al-Hemedawi Ryath, Li Yahui, Yu Jun, Birch David, Chen Yu
Methods and Applications in Fluorescence Vol 8 (2020)
https://doi.org/10.1088/2050-6120/ab854e
TCSPC camera for real time video rate FLIM acquisition based on CMOS technology
Hungerford Graham, McLoskey David, Hirsch Richard, Yip Philip, Birch David, Johnston Nick, Henderson Robert
, pp. 308a-308a (2020)
https://doi.org/10.1016/j.bpj.2019.11.1738
Phenotypic analysis of extracellular vesicles: a review on the applications of fluorescence
Panagopoulou Maria S, Wark Alastair W, Birch David JS, Gregory Christopher D
Journal of Extracellular Vesicles Vol 9 (2020)
https://doi.org/10.1080/20013078.2019.1710020
MAF leads fluorescence into the new decade
Birch David J S, Levitus Marcia, Mely Yves
Methods and Applications in Fluorescence Vol 8 (2019)
https://doi.org/10.1088/2050-6120/ab5b86
Cu2+ effects on beta‐amyloid oligomerisation monitored by fluorescence of intrinsic tyrosine
Alghamdi Abeer, Wellbrock Thorben, Birch David JS, Vyshemirsky Vladislav, Rolinski Olaf J
ChemPhysChem Vol 20, pp. 3181-3185 (2019)
https://doi.org/10.1002/cphc.201900565
Tracking insulin glycation in real time by time-resolved emission spectroscopy
Chung Li Hung C, Birch David J S, Vyshemirsky Vladislav, Ryadnov Maxim G, Rolinski Olaf J
Journal of Physical Chemistry B Vol 123, pp. 7812-7817 (2019)
https://doi.org/10.1021/acs.jpcb.9b06363

more publications

Professional activities

PhD External Examiner
Examiner
22/1/2020
FluoroFest
Chair
24/4/2017
Science Foundation Ireland (External organisation)
Member
2014
Methods and Applications in Fluorescence (Journal)
Editor
1/7/2012
Measurement Science and Technology (Journal)
Editor
1/1/2012
Nano Meets Spectroscopy
Organiser
15/9/2011

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Projects

Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan
Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator)
01-Jan-2017 - 01-Jan-2021
(Horiba Contribution) Initialising multiplexed time-correlated single-photon timing fluorescence systems
Birch, David (Principal Investigator)
01-Jan-2016 - 31-Jan-2016
Elucidating biomolecular self-assembly pathways
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2019
Time-correlated single-photon counting (SUPA INSPIRE)
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2015
Nanometrology for Molecular Science, Medicine & Manufacture
Birch, David (Principal Investigator)
01-Jan-2014 - 30-Jan-2015
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic)
Birch, David (Principal Investigator) Dawson, Martin (Principal Investigator) Dawson, Martin (Principal Investigator) Strain, Michael (Principal Investigator) Chen, Yu (Co-investigator) Gu, Erdan (Co-investigator) Li, David (Co-investigator) Strain, Michael (Co-investigator) Watson, Ian (Co-investigator) Jeffers, John (Researcher) Oppo, Gian-Luca (Researcher) Yao, Alison (Researcher)
01-Jan-2014 - 31-Jan-2019

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