Professor David Birch

Emeritus Professor

Physics

Personal statement

David Birch has been Professor of Photophysics since 1993 having cofounded the Photophysics Group in 1978. His research focuses on fluorescence probes and their application to interdisciplinary molecular grand challenges at the biomedical interface. The Group has raised many millions of pounds of research funding and collaborates with an extensive network of national and international partners across industry and universities. It has successfully trained over 70 research students and post-doctoral fellows, 7 later becoming full professors and others leaders of industry.

David grew up in the Lancashire village of Burscough and then went on to study for his BSc and PhD in the Physics Department at the University of Manchester. He lectured there for one year before moving into industry to work in organic mass spectrometry with VG Micromass Ltd. While at VG he recognised the commercial potential of his PhD for which he had designed and built a novel time-correlated single-photon counting (TCSPC) fluorescence lifetime spectrometer. On arrival at Strathclyde he started to convert his PhD into what were to become world-leading products though IBH, the company he co-founded in 1977. IBH was Strathclyde's first spin-out and one of earliest in Scotland.  He is a pioneer of modern-day fluorescence lifetime spectroscopy and a driving force that has helped make Scotland their global manufacturing hub by having successfully bridged the Industry-University divide for over 40 years as a Company Director and Academic. IBH merged with HORIBA in 2003 and together they are now the market leader in fluorescence spectroscopy. 

David's innovations in measurement are contributing to a wide range of applications, many of critical importance in understanding the molecular science which underpins healthcare. In recent years  his research has focused on biomolecular structure and dynamics down to the single molecule level; melanin structure, photophysics and melanoma; fluorescence guided surgery; glucose sensing for diabetes; aggregation leading to fibrils e.g. beta-amyloid and Alzheimer’s disease; gold nanoparticle photophysics and its application to sensing, imaging and fluid biopsy and 1-10 nm nanoparticle metrology. A list of David's publications is available.

His contributions have been recognised internationally through numerous awards and appointments. In 2017 David was awarded the HORIBA Lifetime Achievement Award for 40 years innovation in TCSPC with the Institute of Physics Dennis Gabor Medal and Prize  for pioneering the UK fluorescence lifetime industry following in 2020. In 2019 IBH was awarded the Institute of Physics Business Innovation Award for the development of the FLIMera multiplexed TCSPC molecular movie camera.  Previously IBH won SMART, SPUR, John Logie Baird and Millennium awards for innovation. 

David is a Fellow of Scotland's National Academy, the Royal Society of Edinburgh, the Institute of Physics and the Royal Society of Chemistry. Since 2002 he has been the Visiting Professor of Applied Physics at the Czech Technical University in Prague. In 1998-99 he held the Sir C V Raman Endowment Chair at the University of Madras and in 2000 Visiting Professor at Kyoto Institute of Technology. In 2014 he was appointed to the Green Honors Chair in Physics at Texas Christian University in Fort Worth. He has held research fellowships from the Royal Society, the Nuffield Foundation and the Japanese Society for the Promotion of Science. 

He was Editor-in-Chief of Measurement Science and Technology from 2012-2016. The journal was launched in 1923 as the world's first measurement journal and the first research journal produced by the Institute of Physics. Presently he is founding co-Editor-in-Chief of Methods and Applications in Fluorescence. He was a member of the Editorial Board of SPIE's Journal of Biomedical Optics from its launch in 1996 until 2019. David served as Head of Department from 2004-10, a period building up to the Government-led REF 2014 assessment from which the Times Higher Education ranked Strathclyde as the number one UK university for Physics Research. As HoD David helped launch the very successful Scottish Universities Physics Alliance (SUPA) in 2004 and represented Strathclyde in helping to win £48m second round SFC funding for SUPA. 

David convened the session on Photochemistry, Photophysics and Electrochemistry at the 7th EuCheMS Congress in Liverpool in August 2018. He launched the FluoroFest Series of International Workshops in Prague in 2009 and Chaired the 12th FluoroFest held in Glasgow in 2017. The latest in the series was held in Fort Worth in May 2019.

profile of David's career has recently been written by Wiley Analytical Science. 

Publications

Fluorescence guided surgery
Stewart Hazel L, Birch David J S
Methods and Applications in Fluorescence Vol 9 (2021)
https://doi.org/10.1088/2050-6120/ac1dbb
Detecting beta-amyloid glycation by intrinsic fluorescence - understanding the link between diabetes and Alzheimer's disease
Alghamdi Abeer, Forbes Shareen, Birch David JS, Vyshemirsky Vladislav, Rolinski Olaf J
Archives of Biochemistry and Biophysics Vol 704 (2021)
https://doi.org/10.1016/j.abb.2021.108886
MAF and fluorescence play their part
Birch David J S, Levitus Marcia, Mély Yves
Methods and Applications in Fluorescence Vol 9 (2021)
https://doi.org/10.1088/2050-6120/abce06
Characterization of single channel liquid light guide coupling and SPAD array imaging for tumour margin estimation using fluorescence lifetime
Stewart Hazel L, Hungerford Graham, Birch David J S
Measurement Science and Technology Vol 31 (2020)
https://doi.org/10.1088/1361-6501/aba5c6
Influence of local microenvironment on the double hydrogen transfer in porphycene
Kasprzycki Piotr, Kopyck Przemysław, Listkowski Arkadiusz, Gorski Aleksander, Radzewicz Czesław, Birch David J S, Waluk Jacek, Fita Piotr
Physical Chemistry Chemical Physics Vol 22, pp. 17117-17128 (2020)
https://doi.org/10.1039/D0CP02687E
A rapid analysis platform for investigating the cellular locations of bacteria using two-photon fluorescence lifetime imaging microscopy
Sapermsap Natakorn, Li David Day-Uei, Al-Hemedawi Ryath, Li Yahui, Yu Jun, Birch David, Chen Yu
Methods and Applications in Fluorescence Vol 8 (2020)
https://doi.org/10.1088/2050-6120/ab854e

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Professional activities

MSc External Examiner
Examiner
6/2021
PhD External Examiner
Examiner
22/1/2020
FluoroFest
Chair
24/4/2017
Science Foundation Ireland (External organisation)
Member
2014
Methods and Applications in Fluorescence (Journal)
Editor
1/7/2012
Measurement Science and Technology (Journal)
Editor
1/1/2012

More professional activities

Projects

Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan
Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator)
01-Jan-2017 - 01-Jan-2021
(Horiba Contribution) Initialising multiplexed time-correlated single-photon timing fluorescence systems
Birch, David (Principal Investigator)
01-Jan-2016 - 31-Jan-2016
Elucidating biomolecular self-assembly pathways
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2019
Time-correlated single-photon counting (SUPA INSPIRE)
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2015
Nanometrology for Molecular Science, Medicine & Manufacture
Birch, David (Principal Investigator)
01-Jan-2014 - 30-Jan-2015
Nanoprobes for melanin and melanoma (support for CDT in Medical Imaging)
Birch, David (Principal Investigator) Chen, Yu (Co-investigator) Sutter, Jens (Co-investigator)
01-Jan-2014 - 30-Jan-2018

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