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Prof David Birch

Research Professor

Physics

Personal statement

David Birch leads the Photophysics Group and works with fluorescence to address interdisciplinary molecular grand challenges at the biomedical interface that are relevant to metabolism and disease. The Group is among the pioneers of modern-day fluorescence lifetime spectrometers and the initiators and driving force that has made Scotland their global manufacturing hub. David co-founded IBH, one of the first Scottish University spin-out companies and now, as part of the Horiba Group, the market-leader in fluorescence spectroscopy.

Many of the techniques and instrumentation first published by the Photophysics Group are widely used around the World. The combination of both excitation and emission monochromators in fluorescence lifetime measurement (J. Phy. E. 1977) has become standard practice. Over two decades the coaxial nanosecond flashlamp (Rev. Sci. Instrum. 1981) was the most widely used source for these measurements, eventually being superseded by semiconductor sources, which became particularly important for UV LED excitation of protein fluorescence lifetime (Meas. Sci. Technol. 2004). Multiplexed time-correlated single-photon counting for simultaneous fluorescence decay measurements was invented in the Group and used to demonstrate time-resolved array spectroscopy (J.Phys.E. 1988). In a subsequent collaboration with UMIST the Group published the first ASIC designed for fluorescence, and demonstrated the benefits of multiplexed decay measurements in fluorescence lifetime imaging (Rev. Sci. Instrum. 1996).

Current research includes biomolecular structure and dynamics down to the single molecule level; melanin structure, photophysics and melanoma; glucose sensing for diabetes; aggregation leading to fibrils e.g. beta-amyloid and Alzheimer’s disease; gold nanoparticle photophysics and its application to sensing and imaging; and 1-10 nm nanoparticle metrology. A list of David's publications is available. 

A Graduate of the University of Manchester David is a Fellow of Scotland's National Academy, the Royal Society of Edinburgh, a Director of Horiba Jobin Yvon IBH Ltd and the Visiting Professor of Applied Physics at the Czech Technical University in Prague. He held the Sir C V Raman Endowment Chair at the University of Madras in 1998-99 and previously research fellowships from the Royal Society, the Nuffield Foundation and the Japanese Society for the Promotion of Science. In 2014 he was appointed to the Green Honors Chair in Physics at Texas Christian University in Fort Worth.

He was Editor-in-Chief of Measurement Science and Technology from 2012-2016 and led the journal to its highest impact factor since it was launched in 1923 as the world's first measurement journal and the first research journal produced by the Institute of Physics. Presently he is co-founding Editor-in-Chief of Methods and Applications in Fluorescence, one of the Institute's newest journals. He has been a member of the Editorial Board of SPIE's Journal of Biomedical Optics since its launch in 1996. David served as Head of Department from 2004-10, a period building up to and including 2.5 years of the Government-led REF 2014 assessment from which the Times Higher Education ranked Strathclyde as the number one in the UK for Physics Research.

David was Chair of the 12th FluoroFest International Workshop held in Glasgow on April 24-26, 2017 where he received the Horiba Lifetime Achievement Award for 40 years of innovation in time-correlated single-photon counting.

 

Publications

A surface plasmon enhanced FLIM-FRET imaging approach based on Au nanoparticles
Zhang Yinan, Chen Yu, Yu Jun, Birch David JS
Medical Devices and Diagnostic Engineering Vol 2, pp. 78-82, (2017)
http://dx.doi.org/10.15761/MDDE.1000119
A lifetime in fluorescence : its measurement and application
Birch David
FluoroFest, (2017)
Outgoing Editor-in-Chief : exciting times at Measurement Science and Technology!
Birch David J S
Measurement Science and Technology Vol 28, pp. 1, (2017)
http://dx.doi.org/10.1088/1361-6501/28/1/010101
Building a quality home for fluorescence
Birch David, Mely Yves , Wolfbeis Otto
Methods and Applications in Fluorescence Vol 4, (2016)
Hairpin DNA functionalized gold nanorods for mRNA detection in homogenous solution
Wei Guoke, Yu Jun, Wang Jinliang, Gu Peng, Birch David J.S., Chen Yu
Journal of Biomedical Optics Vol 21, (2016)
http://dx.doi.org/10.1117/1.JBO.21.9.097001
Probing the sudlow binding site with warfarin : how does gold nanocluster growth alter human serum albumin?
Russell B. A., Mulheran P. A., Birch D. J. S., Chen Y.
Physical Chemistry Chemical Physics Vol 18, pp. 22874-22878, (2016)
http://dx.doi.org/10.1039/C6CP03428D

more publications

Professional activities

FluoroFest
Chair
24/4/2017
Science Foundation Ireland (External organisation)
Member
2014
Methods and Applications in Fluorescence (Journal)
Editor
1/7/2012
Measurement Science and Technology (Journal)
Editor
1/1/2012
Nano Meets Spectroscopy
Organiser
15/9/2011
Royal Society (External organisation)
Member
2011

more professional activities

Projects

Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan
Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator)
Period 01-Oct-2017 - 01-Oct-2020
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-202
Birch, David (Principal Investigator) Chen, Yu (Co-investigator) Li, David (Co-investigator)
Period 01-Oct-2014 - 30-Sep-2019
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-104
Birch, David (Principal Investigator)
Period 01-Oct-2014 - 30-Sep-2019
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic) / R140296-106
Birch, David (Principal Investigator) Chen, Yu (Co-investigator) Li, David (Co-investigator)
Period 01-Oct-2014 - 30-Sep-2019
Elucidating biomolecular self-assembly pathways
Birch, David (Principal Investigator)
Period 01-Oct-2015 - 30-Sep-2019
(Horiba Contribution) Initialising multiplexed time-correlated single-photon timing fluorescence systems
Birch, David (Principal Investigator)
Period 01-Jan-2016 - 31-May-2016

more projects