Professor David Birch

Research Professor


Personal statement

David Birch leads the Photophysics Group and works with fluorescence to address interdisciplinary molecular grand challenges at the biomedical interface that are relevant to metabolism and disease. The Group is among the pioneers of modern-day fluorescence lifetime spectrometers and the initiators and driving force that has made Scotland their global manufacturing hub. David co-founded IBH in 1977 as one of the first Scottish University spin-out companies and for over 40 years he has successfully bridged the Industry-University divide as a Company Director and Academic. As part of the HORIBA Group IBH is now the market-leader in fluorescence spectroscopy.

Many of the techniques and instrumentation first published by the Photophysics Group are widely used around the World. The combination of both excitation and emission monochromators in fluorescence lifetime measurement (J. Phy. E. 1977) has become standard practice. Over two decades the coaxial nanosecond flashlamp source (Rev. Sci. Instrum. 1981) was widely used for these measurements, eventually being superseded by semiconductor sources, which became particularly important for UV LED excitation of protein fluorescence lifetime (Meas. Sci. Technol. 2004). Multiplexed time-correlated single-photon counting for simultaneous fluorescence decay measurements was invented in the Group and used to demonstrate time-resolved array spectroscopy (J.Phys.E. 1988). In a subsequent collaboration with UMIST the Group published the first ASIC designed for fluorescence, and demonstrated the benefits of multiplexed decay measurements in fluorescence lifetime imaging (Rev. Sci. Instrum. 1996). 

Current research includes biomolecular structure and dynamics down to the single molecule level; melanin structure, photophysics and melanoma; glucose sensing for diabetes; aggregation leading to fibrils e.g. beta-amyloid and Alzheimer’s disease; gold nanoparticle photophysics and its application to sensing and imaging; and 1-10 nm nanoparticle metrology. A list of David's publications is available. 

A Graduate of the University of Manchester David is a Fellow of Scotland's National Academy, the Royal Society of Edinburgh, a Director of HORIBA Jobin Yvon IBH Ltd and the Visiting Professor of Applied Physics at the Czech Technical University in Prague. He held the Sir C V Raman Endowment Chair at the University of Madras in 1998-99 and previously research fellowships from the Royal Society, the Nuffield Foundation and the Japanese Society for the Promotion of Science. In 2014 he was appointed to the Green Honors Chair in Physics at Texas Christian University in Fort Worth. In 2017 he received the HORIBA Lifetime Achievement Award for 40 years of innovation in time-correlated single-photon counting.

David was Editor-in-Chief of Measurement Science and Technology from 2012-2016 and led the journal to its highest impact factor since it was launched in 1923 as the world's first measurement journal and the first research journal produced by the Institute of Physics. Presently he is co-founding Editor-in-Chief of Methods and Applications in Fluorescence, one of the Institute's newest journals. He has been a member of the Editorial Board of SPIE's Journal of Biomedical Optics since its launch in 1996. David served as Head of Department from 2004-10, a period building up to and including 2.5 years of the Government-led REF 2014 assessment from which the Times Higher Education ranked Strathclyde as the number one in the UK for Physics Research.

David convened the session on Photochemistry, Photophysics and Electrochemistry at the 7th EuCheMS Congress in Liverpool in August 2018. He launched the FluoroFest Series of International Workshops in Prague in 2009 and Chaired the 12th FluoroFest held in Glasgow in 2017. The next in the series will be held in Fort Worth in May 2019.



A 192x128 time correlated SPAD image sensor in 40nm CMOS technology
Henderson Robert K, Johnston Nick, Mattioli Della Rocca Francesco, Chen Haochang, Li David Day-Uei, Hungerford Graham, Hirsch Richard, McLoskey David, Yip Philip, Birch David JS
IEEE Journal of Solid-State Circuits (2019)
Probing pheomelanin synthesis using thioflavin T fluorescence
Davy Alastair Douglas, Birch David
SPIE Proceedings volume 10893 SPIE Photonics WEST 2019 BIOS (2019)
Fluorescence spans the globe
Birch David J S, Mely Yves , Wolfbeis Otto
Methods and Applications in Fluorescence Vol 7, pp. 1-2 (2019)
Detecting Lysozyme unfolding via the fluorescence of Lysozyme encapsulated gold nanoclusters
Alkudaisi Nora, Russell Ben A, Jachimska Barbara, Birch David J S, Chen Yu
Journal of Materials Chemistry B, pp. 1-10 (2019)
Evidence for pheomelanin sheet structure
Davy A D, Birch D J S
Applied Physics Letters Vol 113 (2018)
A 192 x 128 time correlated single photon counting imager in 40nm CMOS technology
Henderson Robert K, Johnston Nick, Chen Haochang, Li David Day-Uei, Hungerford Graham, Hirsch Richard, Yip Philip, McLoskey David, Birch David
44th European Solid-State Circuits Conference (ESSCIRC) 2018 44th European Solid-State Circuits Conference (2018)

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Professional activities

Science Foundation Ireland (External organisation)
Methods and Applications in Fluorescence (Journal)
Measurement Science and Technology (Journal)
Nano Meets Spectroscopy
Masao Horiba Award (Event)

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Doctoral Training Partnership (DTP 2016-2017 University of Strathclyde) | Adelt, Milan
Chen, Yu (Principal Investigator) Birch, David (Co-investigator) Adelt, Milan (Research Co-investigator)
01-Jan-2017 - 01-Jan-2021
(Horiba Contribution) Initialising multiplexed time-correlated single-photon timing fluorescence systems
Birch, David (Principal Investigator)
01-Jan-2016 - 31-Jan-2016
Elucidating biomolecular self-assembly pathways
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2019
Time-correlated single-photon counting (SUPA INSPIRE)
Birch, David (Principal Investigator)
01-Jan-2015 - 30-Jan-2015
Nanometrology for Molecular Science, Medicine & Manufacture
Birch, David (Principal Investigator)
01-Jan-2014 - 30-Jan-2015
UK Quantum Technology Hub in Quantum Enhanced Imaging (Quantic)
Birch, David (Principal Investigator) Dawson, Martin (Principal Investigator) Dawson, Martin (Principal Investigator) Strain, Michael (Principal Investigator) Chen, Yu (Co-investigator) Gu, Erdan (Co-investigator) Li, David (Co-investigator) Strain, Michael (Co-investigator) Watson, Ian (Co-investigator) Jeffers, John (Researcher) Oppo, Gian-Luca (Researcher) Yao, Alison (Researcher)
01-Jan-2014 - 31-Jan-2019

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