PAC Mass Spectrometry FacilityFacility Management
Dr. Jessica R. Bame has 15 years of experience in applying mass spectrometry, chromatography and NMR to a wide variety of analytical applications. She worked in collaboration with RTI International and the University of North Carolina at Greensboro for 4 years in natural product drug discovery, isolating and identitying a previous unknown efflux pump inhibitor against S. aureus in Alkanna Orientalis. She moved to the Georgia Institute of Technology working with the CDC and international partners to further develop MS/MS detection methodologies for sphingolipids in mouse/human tissue samples. She obtained her PhD at the University of Bristol focusing in NMR, developing techniques for quantitative distance determination via NOE. With this wide variety of skills, she worked for 3 years at the University of Glasgow under Professor Leroy Cronin as part of a project team developing a metric for chemical space complexity quantification via NMR, IR and Mass Spectrometry to be used by international space agencies. In addition, she co-managed a 600 MHz NMR for a highly discipline diverse team of 70 researchers, performing experimental optimisation and development to assisting team in approach to analytical research. Now she is a co-manager of the PAC Mass Spectrometry Facility at the University of Strathclyde along with a lecturer of 3rd year undergraduate students in mass spectrometry theory and applications.
Dr Graeme J. Anderson has more than 25 years experience in applying mass spectrometry, NMR, circular dichroism, surface plasmon resonance (SPR) and Fourier-transform infra-red (FTIR) to the analysis of biomolecules such as peptides, proteins, antibodies, antibody fragments and antibody-drug conjugates.
He graduated from St. Andrews University with a First Class Degree in Chemistry and studied for a PhD. at the School of Pharmacy, University of London under the supervision of Professor W.A. Gibbons, focusing on the synthesis and conformation studies of renin peptide inhibitors.
Graeme moved to Manchester Metropolitan University where he lectured in Organic Chemistry before moving to work in industry at BioReliance, first as Senior Scientist within the viral clearance group and then Team Leader within the Analytical Chemistry department, running a laboratory performing lot release and stability testing of engineered antibodies to GMP regulatory standard.
He moved to Sartorius (previously BioOutsource) to manage their Biophysical Services department, overseeing the development and validation of assays to GMP regulatory standard, lot release testing and stability studies of antibody and biosimilar products using UHPLC-MS, capillary electrophoresis (CE) and SPR techniques.
He now co-manages the PAC Mass Spectrometry Facility department with his colleague Dr Jessica Bame.