The Mass Spectrometry facility within the Chemistry Department at the University of Strathclyde provides analysis of novel synthesised compounds, large and small molecules covering a mass range of 50- 150,000Da, depending on the instrument employed.
This technique is ideal for separating and identifying components in volatile and semivolatile organic compounds in complex mixtures in the gas phase.
High Performance Liquid Chromatography
Separation and identification of a variety of organic compounds, from small molecules to peptides and proteins
Using a Matrix to help the ionisation process, Matrix Assisted Laser Desorption/Ionisation can be used in two different modes: Reflectron Mode for fast analysis of small molecules; and Linear Mode for larger molecules, typically proteins and polymers.
|Ionisation mode||Instrument||Technique||Mass range|
|Electron Ionisation (EI ion trap)||Thermo Finnigan Polaris Q||GCMS||(50-650Da)|
|Chemical Ionisation (CI)||Agilent 5975C||GCMS||(50-1000Da)|
|Electrospray Ionisation (ESI ion trap)||Thermo Finnigan LCQ DUO||Direct Infusion||(50-2000Da)|
|Multimode Ionisation (ESI/APCI)||Agilent 6130||Coupled with Agilent 1200LC||(50-2000Da)|
|Time of Flight (TOF)||Kratos Axima CFR||MALDI –TOF||(20-150,000Da)|
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Please contact us in the first instance to discuss your requirements.