Postgraduate research opportunities Identification of novel therapies targeting the right ventricle in pulmonary arterial hypertension
ApplyKey facts
- Opens: Monday 20 May 2024
- Deadline: Saturday 20 July 2024
- Number of places: 1
- Duration: 36 months
- Funding: Home fee, Stipend
Overview
Pulmonary arterial hypertension (PAH) is a fatal, rapidly progressive disease, leading to right ventricular (RV) failure and death. Though the pathology in PAH begins with an obstructive vasculopathy in the lungs, the prognosis is mainly determined by RV function. However, there is no effective drug directly targeting the RV. This project will identify novel therapeutic targets for RV in PAH using both animal model, clinical samples and a range of metabolomics and proteomics technologies.Eligibility
Applicants should have a minimum of a UK Upper Second (2:1) undergraduate degree or equivalent, in Biomedical Sciences, or a strongly related discipline. Applicants will also need to meet the University’s English Language requirements. A strong background in cardiovascular pathophysiology, experience in in vivo animal study, experience in biological studies such as IHC/westernblot, or a Master’s degree in related discipline is a plus.
Project Details
We are seeking a highly-motivated PhD candidate starting from 1st of October, 2024 to work on a project focused on identifying novel therapies targeting the right ventricle (RV) in pulmonary arterial hypertension (PAH). The PhD candidate will be supervised by Dr. Lian Tian (cardiovascular physiology: in vivo and in vitro studies) and Dr. Nicholas Rattray (metabolomics and biomolecular modelling) within Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde.
As a PhD student, you will be fully immersed in a dynamic research environment that fosters both national and international collaboration. And you will have the opportunity to gain skills including in vivo, ex vivo and in vitro experiments, proteomic data analysis, preparing posters and presentation in conferences, and writing peer-reviewed papers.
Further information
Funding details
University of Strathclyde REA studentship, coving full home fee plus standard stipend.
While there is no funding in place for opportunities marked "unfunded", there are lots of different options to help you fund postgraduate research. Visit funding your postgraduate research for links to government grants, research councils funding and more, that could be available.
Supervisors
Dr Nicholas Rattray
Senior Lecturer
Strathclyde Institute of Pharmacy and Biomedical Sciences
Apply
Interested candidates should email the following information in the form of one single PDF file to Dr Lian Tian (lian.tian@strath.ac.uk). Incomplete applications may not be considered.
- CV including the names and contacts of two references.
- Cover letter describing your academic achievements, research interests, future career goals, and why you are interested in joining our research group.
- Most recent undergraduate and Master (if applicable) transcripts. Unofficial transcripts are acceptable at this stage.
Number of places: 1
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