Research in chemical biology and medicinal chemistry encompasses a broad spectrum of interests from the delivery of chemical tools to underpin and advance basic biology, to the application of knowledge in drug discovery.
Our specific skills lie in synthesis, isotopic labelling, bioinformatics, nucleic acid chemistry, amino acid chemistry, heterocyclic chemistry, biophysical chemistry and NMR spectroscopy.
Within medicinal chemistry, there is great interest in developing therapeutics, including antimicrobials and anticancer agents.
Members of the Section are embedded within the GSK-University of Strathclyde Collaborative MPhil and PhD Programme, which to date has trained >200 scientists, resulting in >180 research outputs and students have been awarded >200 national and international prizes in recognition of their work.
| Staff members |
Research interests |
|
Dr Rebecca Beveridge
|
- analytical chemistry
- ion mobility-mass spectrometry
- protein structure and dynamics
- biomolecular interactions
|
| Professor Glenn A. Burley |
- alternative splicing therapies
- bioconjugation
- chemistry of nucleosides
- gene expression
- nucleic acid chemical biology
|
| Dr Shiao Chow |
- catalysis
- organic synthesis
- bioorthogonal chemistry
- medicinal chemistry
|
| Dr Mark J. Dufton |
- bioinformatics
- biomolecular structure and mechanism
- drug discovery
|
| Dr Robert Edkins |
- luminescence spectroscopy
- synthesis of fluorescent imaging agents and molecular probes
- photodynamic and photothermal therapies
|
| Dr Craig Jamieson |
- catalysis
- chemical biology
- drug discovery
- medicinal chemistry
- organic synthesis
|
| Professor William J. Kerr |
- asymmetric synthesis
- catalysis
- organometallic chemistry
- isotopic labelling
- total synthesis
|
| Dr David Lindsay |
- organometallic chemistry
- catalysis
- reaction mechanism and kinetics
- C-H activation
- asymmetric synthesis
|
| Dr Barry D. Moore |
- biophysical chemistry
- non-aqueous biocatalysis
- self-assembly
- mechanisms of crystal formation
- PCMC
- CaP-PCMC
- formulation of therapeutic proteins and vaccines
|
| Dr John A. Parkinson |
- solution phase NMR
- experimental NMR methods
- NMR instrumentation
- NMR data handling and interpretation
|
| Professor Colin J. Suckling |
- drug discovery
- medicinal chemistry
- heterocycle synthesis
|
| Professor Nick C. O. Tomkinson |
- catalysis
- chemical biology
- medicinal chemistry
- organic synthesis
|
| Dr Fraser Scott |
- medicinal chemistry
- drug discovery
- chemical biology
- anti-infectives
|